"FAM19A2" Related Products


Recombinant Human FAM19A2

Cat.No.: FAM19A2-609H
Product Overview: Recombinant Human FAM19A2 produced in E. coli is approximately 11.2 kDa, a single, non-glycosylated polypeptide chain containing 101 amino acids.
Description: TAFA-2 also named FAM19A2 belongs to the TAFA family of chemokine-like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature TAFA1 to 4 contain 10 regularly spaced cysteine residues. Human TAFA2 is 97% aa identical to mouse TAFA2. TAFA2 expression can be detected in the central nervous system (CNS), colon, heart, lung, spleen, kidney, and thymus, but its expression in the CNS is 50- to 1000-fold higher than in other tissues. Within the CNS, TAFA2 expression is highest in the occipital and frontal cortex (3- to 10-fold moreabundantly expressed than in other cortical regions) and medulla. The biological functions of TAFA family members remain to be determined, but there are a few tentative hypotheses.
Source: E. coli
Species: Human
Form: Lyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, pH 7.4.
Bio-activity: Fully biologically active when compared to standard. The biologically active is determined by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. rHuTAFA-2, immobilized at 624 μg/mL on a 96 well plate, is able to significantly enhance neurite outgrowth.
Molecular Mass: 11.2 kDa
Endotoxin: Less than 1 EU/μg of rHuTAFA-2/FAM19A2 as determined by LAL method.
Purity: >95% by SDS-PAGE and HPLC analyses.
Usage: This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Storage: This lyophilized preparation is stable at 2-8 centigrade, but should be kept at -20 centigrade for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 centigrade. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 centigrade to -70 centigrade. Avoid repeated freeze/thaw cycles.
Reconstitution: We recommend that this vial be briefy centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name: FAM19A2 family with sequence similarity 19 (chemokine (C-C motif)-like), member A2 [ Homo sapiens ]
Official Symbol: FAM19A2
Synonyms: FAM19A2; family with sequence similarity 19 (chemokine (C-C motif)-like), member A2; protein FAM19A2; TAFA 2; chemokine-like protein TAFA-2; TAFA2; TAFA-2; MGC42403; DKFZp761E1217; DKFZp781P0552;
Gene ID: 338811
mRNA Refseq: NM_178539
Protein Refseq: NP_848634
UniProt ID: Q8N3H0
Chromosome Location: 12q14.1

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