"PRKD2" Related Products

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Recombinant Human PRKD2, GST-tagged

Cat.No. : PRKD2-151H
Product Overview : Recombinant full-length human PKD2 (G848E) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : PKD2(G870E) is a glycine to glutamic acid mutation at 870 aa in PKD2 and appears as a somatic mutation in gastric adenocarcinoma samples. PKD2 is a member of the polycystin protein family and is involved in calcium transport and calcium signaling in renal epithelial cells. PKD2 interacts with polycystin 1 and this complex may be partners in a common signaling cascade involved in tubular morphogenesis. PKD2 may function as a chaperone-like molecule, which may prevent ERAD of PKD2. PKD2 form an interaction network with PKD1 as the rate-limiting component.
Source : Sf9 insect cells using baculovirus
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : The specific activity of PKD2 (G848E) was determined to be 330 nmol /min/mg
Molecular Mass : ~130 kDa
Purity : >90% by densitometry
Applications : Kinase Assay, Western Blot
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 μg/μl
Gene Name : PRKD2 protein kinase D2 [ Homo sapiens ]
Official Symbol : PRKD2
Synonyms : PRKD2; protein kinase D2; serine/threonine-protein kinase D2; DKFZP586E0820; HSPC187; PKD2; nPKC-D2;
Gene ID : 25865
mRNA Refseq : NM_001079880
Protein Refseq : NP_001073349
MIM : 607074
UniProt ID : Q9BZL6
Chromosome Location : 19q13.2
Pathway : T Cell Receptor Signaling Pathway, organism-specific biosystem;
Function : ATP binding; metal ion binding; nucleotide binding; protein binding; protein kinase C activity; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity;

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