"AXL" Related Products

Expand
Expand

Recombinant Human AXL (R499C), GST-tagged

Cat.No.: AXL-202H
Product Overview: Recombinant human AXL (R499C) (473-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: AXL, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase which is a member of the TAM (TYRO3/AXL/MER) receptor tyrosine kinase subfamily. AXL represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats and Axl transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. AXL is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding.
Source: Sf9 insect cells using baculovirus
Species: Human
Tag: GST
Form: Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity: The specific activity of AXL (R499C) was determined to be 3 nmol /min/mg
Molecular Mass: ~76 kDa
Purity: >85% by densitometry
Applications: Kinase Assay, Western Blot
Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration: 0.1 μg/μl
Gene Name: AXL AXL receptor tyrosine kinase [ Homo sapiens ]
Official Symbol: AXL
Synonyms: AXL; AXL receptor tyrosine kinase; tyrosine-protein kinase receptor UFO; JTK11; UFO; AXL oncogene; oncogene AXL; AXL transforming sequence/gene;
Gene ID: 558
mRNA Refseq: NM_001699
Protein Refseq: NP_001690
MIM: 109135
UniProt ID: P30530
Chromosome Location: 19q13.1
Function: ATP binding; nucleotide binding; protein heterodimerization activity; receptor activity; transmembrane receptor protein tyrosine kinase activity;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.