Recombinant Human KDM2A, GST-tagged
Cat.No. : | KDM2A-213H |
Product Overview : | Recombinant human KDM2A (1-748) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | KDM2A or lysine (K)-specific demethylase 2A is a member of the F-box protein family that are components of the modular E3 ubiquitin protein ligases called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. KDM2A belongs to the Fbls class and, in addition to the presence of an F-box, contains at least six highly degenerated leucine-rich repeats which play a role in epigenetic silencing. The demethylase activity of the JmjC domain-containing proteins is conserved from yeast to human. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM sodium phosphate, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~115 kDa |
Purity : | >90% by densitometry |
Applications : | Western Blot |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | KDM2A lysine (K)-specific demethylase 2A [ Homo sapiens ] |
Official Symbol : | KDM2A |
Synonyms : | KDM2A; lysine (K)-specific demethylase 2A; F box and leucine rich repeat protein 11 , FBXL11; lysine-specific demethylase 2A; CXXC8; DKFZP434M1735; F box protein FBL11; FBL7; FBL11; FLJ00115; JHDM1A; jumonji C domain containing histone demethylase 1A; KIAA1004; LILINA; F-box/LRR-repeat protein 11; CXXC-type zinc finger protein 8; [Histone-H3]-lysine-36 demethylase 1A; F-box and leucine-rich repeat protein 11; jumonji C domain-containing histone demethylase 1A; jmjC domain-containing histone demethylation protein 1A; FBXL11; FLJ46431; DKFZp434M1735; |
Gene ID : | 22992 |
mRNA Refseq : | NM_001256405 |
Protein Refseq : | NP_001243334 |
MIM : | 605657 |
UniProt ID : | Q9Y2K7 |
Chromosome Location : | 11q13.1 |
Function : | DNA binding; histone demethylase activity (H3-K36 specific); metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; zinc ion binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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