"RNASE3" Related Products


Recombinant Human RNASE3, His-tagged

Cat.No.: RNASE3-5319H
Product Overview: Recombinant Human Ribonuclease 3/RNASE3 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Arg28-Ile160) of Human RNASE3 fused with a 6His tag at the C-terminus.
Description: Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Source: HEK293
Species: Human
Tag: His
Endotoxin: Less than 0.1 ng/μg (1 IEU/μg).
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Shipping: The product is shipped on dry ice/ice packs.
Gene Name: RNASE3 ribonuclease, RNase A family, 3 [ Homo sapiens (human) ]
Official Symbol: RNASE3
Synonyms: RNASE3; ECP; RNS3; ribonuclease, RNase A family, 3; eosinophil cationic protein; RNase 3; ribonuclease 3; cytotoxic ribonuclease; EC 3.1.27.-
Gene ID: 6037
mRNA Refseq: NM_002935
Protein Refseq: NP_002926
MIM: 131398
UniProt ID: P12724
Chromosome Location: 14q24-q31
Pathway: Asthma
Function: nucleic acid binding; pancreatic ribonuclease activity; ribonuclease activity

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