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Recombinant Human RNASE3, His-tagged

Cat.No. : RNASE3-5319H
Product Overview : Recombinant Human Ribonuclease 3/RNASE3 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Arg28-Ile160) of Human RNASE3 fused with a 6His tag at the C-terminus.
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  • Gene Information
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Description : Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Source : HEK293
Species : Human
Tag : His
AA Sequence : RPPQFTRAQWFAIQHISLNPPRCTI AMRAINNYRWRCKNQNTFLRTTFAN VVNVCGNQSIRCPHNRTLNNCHRSR FRVPLLHCDLINPGAQNISNCRYAD RPGRRFYVVACDNRDPRDSPRYPVV PVHLDTTIVDHHHHHH
Endotoxin : Less than 0.1 ng/μg (1 IEU/μg).
Purity : Greater than 95% as determined by reducing SDS-PAGE.
Shipping : The product is shipped on dry ice/ice packs.
Gene Name : RNASE3 ribonuclease, RNase A family, 3 [ Homo sapiens (human) ]
Official Symbol : RNASE3
Synonyms : RNASE3; ECP; RNS3; ribonuclease, RNase A family, 3; eosinophil cationic protein; RNase 3; ribonuclease 3; cytotoxic ribonuclease; EC 3.1.27.-
Gene ID : 6037
mRNA Refseq : NM_002935
Protein Refseq : NP_002926
MIM : 131398
UniProt ID : P12724
Chromosome Location : 14q24-q31
Pathway : Asthma
Function : nucleic acid binding; pancreatic ribonuclease activity; ribonuclease activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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