Active Recombinant Human ANGPTL2, FLAG-tagged

• Cat.No.: ANGPTL2-90H
• Product Overview: Coiled-coil domain of human ANGPTL2 (aa 23-248) is fused at the C-terminus to a FLAG-tag.

Specification

• Species: Human
• Source: HEK293
• Tag: Flag
• Protein Length: 23-248 a.a.
• Description: ANGPTL2 (Angiopoietin-like protein 2) stimulates expansion of HSCs. ANGPTL2 plays an important role in the pathogenesis of diabetic glomerulopathy. The upregulation of ANGPTL2 in diabetic glomerulopathy shows a close relationship to abnormal microvasculature and endothelial inflammation.
• Form: Liquid. 0.2μm-filtered solution in PBS.
• Bio-activity: Activates ERK phosphorylation in THP-1 cells.
• Molecular Mass: ~32kDa (SDS-PAGE)
• Endotoxin: <0.1eu g="" purified="" protein="" (lal="" test;="" lonza).="">
• Purity: ≥90% (SDS-PAGE)
• Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.
• Concentration: 0.4 mg/ml

Gene Information

• Gene Name: ANGPTL2 angiopoietin-like 2 [ Homo sapiens ]
• Official Symbol: ANGPTL2
• Synonyms: ANGPTL2; angiopoietin-like 2; angiopoietin-related protein 2; ARP2; HARP; angiopoietin-like protein 2; MGC8889
• Gene ID: 23452
• mRNA Refseq: NM_012098
• Protein Refseq: NP_036230
• MIM: 605001
• UniProt ID: Q9UKU9
• Chromosome Location: 9q34
• Function: receptor binding