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Active Recombinant Mouse Tnfrsf22, Fc-tagged

Cat.No. : Tnfrsf22-212M
Product Overview : The extracellular domain of mouse dcTRAIL-R2 (aa 41-171) is fused to the Fc portion of human IgG1.
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  • Gene Information
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Description : dcTRAIL-R2 is a decoy receptor for the cytotoxic ligand mouse TRAIL. dcTRAIL-R2 binds to mouse and human TRAIL, but is unable of transmitting a signal.The extracellular domains of dcTRAIL-R2 compete with those of death receptor 5 (DR5) for ligand binding and act as decoys that prevent TRAIL from inducing apoptosis through DR5.
Source : HEK293 Cells
Species : Mouse
Tag : Fc
Form : Lyophilized. Contains PBS.
Bio-activity : Blocks human or mouse TRAIL activity. By ELISA, using dcTRAIL-R2 (mouse):Fc (human) (1μg/ml), 50% of the maximal binding of human and mouse TRAIL is observed at about 20-50 ng/ml.
Molecular Mass : ~50kDa (SDS-PAGE)
Purity : ≥95% (SDS-PAGE)
Stability : Stable for at least 6 months after receipt when stored at -20°C.
Storage : Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
Concentration : 1mg/ml after reconstitution.
Gene Name : Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 [ Mus musculus ]
Official Symbol : Tnfrsf22
Synonyms : TNFRSF22; tumor necrosis factor receptor superfamily, member 22; tumor necrosis factor receptor superfamily member 22; TNF receptor homolog 2; decoy TRAIL receptor 2; TNF receptor family member SOBa; tumor necrosis factor receptor p60 homolog 2; tumor necrosis factor receptor superfamily, member 1a-like 2; SOBa; Tnfrh2; Tnfrsf1al2; mDcTrailr2; 2810028K06Rik; C130035G06Rik;
Gene ID : 79202
mRNA Refseq : NM_023680
Protein Refseq : NP_076169
Function : TRAIL binding; binding; protein binding; receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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