"TNFRSF21" Related Products


Recombinant Human TNFRSF21, Fc-tagged

Cat.No.: TNFRSF21-228H
Product Overview: The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351).
Description: DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the β-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.
Source: HEK293 Cells
Species: Human
Tag: Fc
Form: Lyophilized. Contains PBS.
Molecular Mass: ~80kDa (SDS-PAGE)
Purity: ≥95% (SDS-PAGE)
Stability: Stable for at least 6 months after receipt when stored at -20°C.
Storage: Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
Concentration: 1mg/ml after reconstitution.
Gene Name: TNFRSF21 tumor necrosis factor receptor superfamily, member 21 [ Homo sapiens ]
Official Symbol: TNFRSF21
Synonyms: TNFRSF21; tumor necrosis factor receptor superfamily, member 21; tumor necrosis factor receptor superfamily member 21; CD358; death receptor 6; DR6; TNFR-related death receptor 6; BM-018; MGC31965;
Gene ID: 27242
mRNA Refseq: NM_014452
Protein Refseq: NP_055267
MIM: 605732
UniProt ID: O75509
Chromosome Location: 6p21.1
Pathway: Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem;
Function: protein binding; receptor activity;

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