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Recombinant Mouse Parp2, His-tagged

Cat.No.: Parp2-453M
Product Overview: Mouse full-length PARP-2 [ARTD2] is fused to a His-tag.
Description: PARP-2 [ARTD2] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Source: Baculovirus infected Sf21 Cells
Species: Mouse
Tag: His
Form: Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol.
Bio-activity: ≥600U/mg protein.
Purity: ≥98% (SDS-PAGE)
Stability: Stable for at least 6 months after receipt when stored at -80°C.
Storage: Short Term Storage: -20°C; Long Term Storage: -80°C. After opening, prepare aliquots and store at -80°C. Avoid freeze/thaw cycles.
Concentration: Lot dependent (0.2-1mg/ml)
Gene Name: Parp2 poly (ADP-ribose) polymerase family, member 2 [ Mus musculus ]
Official Symbol: Parp2
Synonyms: PARP2; poly (ADP-ribose) polymerase family, member 2; poly [ADP-ribose] polymerase 2; ADPRT-2; mPARP-2; pADPRT-2; poly[ADP-ribose] synthase 2; poly[ADP-ribose] synthetase 2; NAD(+) ADP-ribosyltransferase 2; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 2; ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2; poly(ADP-ribose) polymerase)-like 2; Adprt2; C78626; PARP-2; Adprtl2; Aspartl2;
Gene ID: 11546
mRNA Refseq: NM_009632
Protein Refseq: NP_033762
Pathway: BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem;
Function: DNA binding; NAD+ ADP-ribosyltransferase activity; protein binding; transferase activity; transferase activity, transferring glycosyl groups;

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