|Cat. No. :
|Product Overview :
||Recombinant Human TGF-b 1 (177-391 a.a.) produced inE.coliis purified by standard chromatographic techniques and shows a 51 kDa band on SDS-PAGE (including GST tag).
||Transforming growth factor betas (TGF Betas) mediate many cell-cell interactions that occur during embryonic development. Three TGF Betas have been identified in mammals. TGF Beta 1, TGF Beta 2 and TGF Beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule.
|Physical Appearance :
||Sterile Filtered solution at a concentration of 0.1 mg/ml.
||Greater than 80.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
||The protein solution contains 50mM Tris-Acetate, pH-7.5, 1mM EDTA and 20% Glycerol.
|Amino Acid Sequence :
||The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Asp-Thr-Asn.
||TGF-beta 1 although stable at 4°C for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
|PDB rendering based on 1kla. :