Recombinant Human IGFBP7 IGFBP7-55H

Recombinant Human IGFBP7

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Recombinant Human IGFBP7

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Cat.No. : IGFBP7-55H
Product Overview : Recombinant human IGF-BP7 is a 26.4 kDa protein consisting of 256 amino acid residues.
Description : This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm.
Source : E.coli
Species : Human
Molecular Mass : 26.4 kDa
AA Sequence : SSSDTCGPCE PASCPPLPPL GCLLGETRDA CGCCPMCARG EGEPCGGGGA GRGYCAPGME CVKSRKRRKG KAGAAAGGPG VSGVCVCKSR YPVCGSDGTT YPSGCQLRAA SQRAESRGEK AITQVSKGTC EQGPSIVTPP KDIWNVTGAQ VYLSCEVIGI PTPVLIWNKV KRGHYGVQRT ELLPGDRDNL AIQTRGGPEK HEVTGWVLVS PLSKEDAGEY ECHASNSQGQ ASASAKITVV DALHEIPVKK GEGAEL
Purity : Greater than 98% by SDS-PAGE gel and HPLC analyses.
Gene Name : IGFBP7 insulin-like growth factor binding protein 7 [ Homo sapiens(human) ]
Official Symbol : IGFBP7
Synonyms : IGFBP7; AGM; PSF; TAF; FSTL2; IBP-7; MAC25; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; IGFBP-rP1; angiomodulin; IGF-binding protein 7; PGI2-stimulating factor; tumor-derived adhesion factor; prostacyclin-stimulating factor
Gene ID : 3490
mRNA Refseq : NM_001553
Protein Refseq : NP_001544
MIM : 602867
UniProt ID : Q16270
Chromosome Location : 4q12
Pathway : Senescence and Autophagy
Function : insulin-like growth factor binding; protein binding

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