Recombinant Human KDM1 protein, His-tagged
Cat.No. : | KDM1-299H |
Product Overview : | Recombinant Human KDM1 protein(524-876 aa), fused with His tag, was expressed in E.coli. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole. |
Protein Length : | 524-876 aa |
AA Sequence : | TQGKLEEKLQELEANPPSDVYLSSR DRQILDWHFANLEFANATPLSTLSL KHWDQDDDFEFTGSHLTVRNGYSCV PVALAEGLDIKLNTAVRQVRYTASG CEVIAVNTRSTSQTFIYKCDAVLCT LPLGVLKQQPPAVQFVPPLPEWKTS AVQRMGFGNLNKVVLCFDRVFWDPS VNLFGHVGSTTASRGELFLFWNLYK APILLALVAGEAAGIMENISDDVIV GRCLAILKGIFGSSAVPQPKETVVS RWRADPWARGSYSYVAAGSSGNDYD LMAQPITPGPSIPGAPQPIPRLFFA GEHTIRNYPATVHGALLSGLREAGR IADQFLGAMYTLPRQATPGVPAQQS PSM |
Purity : | 90%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
Storage : | Short-term storage: Store at 2-8°C for (1-2 weeks). Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles. |
Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGenetic changes in KDM1 can lead to dysregulated gene expression and cellular dysfunction.
KDM1 plays a role in modulating hormone-responsive genes, impacting diseases like breast cancer.
It alters epigenetic marks, influencing gene activity and cellular function.
KDM1 can contribute to oncogenesis by modifying expression of cancer-related genes.
KDM1 is involved in histone demethylation, crucial for regulating gene expression.
Targeting KDM1 in cancer can modulate epigenetic marks and tumor growth.
KDM1 affects stem cell differentiation by altering epigenetic landscapes.
Customer Reviews (3)
Write a reviewInstrumental in advancing our protein studies.
Dependable, meets the highest research standards.
Accurate, quick, and cost-effective services.
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