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Recombinant Human KDM1 protein, His-tagged

Cat.No. : KDM1-299H
Product Overview : Recombinant Human KDM1 protein(524-876 aa), fused with His tag, was expressed in E.coli.
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Source : E.coli
Species : Human
Tag : His
Form : The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole.
Protein Length : 524-876 aa
AA Sequence : TQGKLEEKLQELEANPPSDVYLSSR DRQILDWHFANLEFANATPLSTLSL KHWDQDDDFEFTGSHLTVRNGYSCV PVALAEGLDIKLNTAVRQVRYTASG CEVIAVNTRSTSQTFIYKCDAVLCT LPLGVLKQQPPAVQFVPPLPEWKTS AVQRMGFGNLNKVVLCFDRVFWDPS VNLFGHVGSTTASRGELFLFWNLYK APILLALVAGEAAGIMENISDDVIV GRCLAILKGIFGSSAVPQPKETVVS RWRADPWARGSYSYVAAGSSGNDYD LMAQPITPGPSIPGAPQPIPRLFFA GEHTIRNYPATVHGALLSGLREAGR IADQFLGAMYTLPRQATPGVPAQQS PSM
Purity : 90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Storage : Short-term storage: Store at 2-8°C for (1-2 weeks).
Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How do genetic alterations in KDM1 affect its function in cell regulation? 01/31/2023

Genetic changes in KDM1 can lead to dysregulated gene expression and cellular dysfunction.

What is the relationship between KDM1 and hormone-responsive genes in diseases like breast cancer? 08/03/2022

KDM1 plays a role in modulating hormone-responsive genes, impacting diseases like breast cancer.

How does KDM1 influence epigenetic modifications? 03/01/2022

It alters epigenetic marks, influencing gene activity and cellular function.

What role does KDM1 play in cancer development and progression? 11/05/2021

KDM1 can contribute to oncogenesis by modifying expression of cancer-related genes.

What is the primary function of KDM1 in gene regulation? 06/12/2017

KDM1 is involved in histone demethylation, crucial for regulating gene expression.

What are the therapeutic implications of targeting KDM1 in cancer treatment? 06/03/2017

Targeting KDM1 in cancer can modulate epigenetic marks and tumor growth.

How does KDM1 activity impact stem cell differentiation and development? 02/16/2017

KDM1 affects stem cell differentiation by altering epigenetic landscapes.

Customer Reviews (3)

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10/12/2022

    Instrumental in advancing our protein studies.

    05/03/2020

      Dependable, meets the highest research standards.

      02/15/2018

        Accurate, quick, and cost-effective services.

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