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Recombinant Human MUTYH, His-tagged

Cat.No. : MUTYH-1116H
Product Overview : Recombinant Human MUTYH protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Source : E.coli
Species : Human
Tag : His
Protein length : 187-535aa
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : MUTYH mutY homolog (E. coli) [ Homo sapiens ]
Official Symbol : MUTYH
Synonyms : MUTYH; mutY homolog (E. coli); mutY (E. coli) homolog; A/G-specific adenine DNA glycosylase; MYH; CYP2C; MGC4416;
Gene ID : 4595
mRNA Refseq : NM_001048171
Protein Refseq : NP_001041636
MIM : 604933
UniProt ID : Q9UIF7
Chromosome Location : 1p34.1
Pathway : Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Base-Excision Repair, AP Site Formation, organism-specific biosystem; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway, organism-specific biosystem; Cleavage of the damaged purine, organism-specific biosystem; DNA Repair, organism-specific biosystem;
Function : 4 iron, 4 sulfur cluster binding; NOT MutLalpha complex binding; NOT MutLbeta complex binding; MutSalpha complex binding; NOT MutSbeta complex binding; catalytic activity; endonuclease activity; hydrolase activity, acting on glycosyl bonds; metal ion bind

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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