Active Recombinant Human TIGIT, Fc-tagged
Cat.No. : | TIGIT-105H |
Product Overview : | Recombinant Human TIGIT (Met22-Pro141) with Fc tag was expressed in CHO Cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses. |
Source : | CHO Cells |
Species : | Human |
Tag : | Fc |
Predicted N Terminal : | Met22 |
Form : | Lyophilized from a 0.2 μm filtered solution in PBS.? |
Bio-activity : | Measured by its binding ability in a functional ELISA. When Recombinant Human CD155/PVR is coated at 2.5?μg/mL (100?μL/well), the concentration of Recombinant Human TIGIT Fc Chimera that produces 50%?optimal binding response is typically?20-100 ng/mL. |
Molecular Mass : | 39.6 kDa (monomer) |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 °C as supplied.1 month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to -70 °C under sterile conditions after reconstitution. |
Reconstitution : | Reconstitute at 100 μg/mL in PBS. |
Gene Name : | TIGIT?T cell immunoreceptor with Ig and ITIM domains [?Homo sapiens?(human) ] |
Official Symbol : | TIGIT |
Synonyms : | TIGIT; VSIG9; VSTM3; WUCAM; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; V-set and transmembrane domain containing 3; V-set and immunoglobulin domain containing 9; Washington University cell adhesion molecule; V-set and transmembrane domain-containing protein 3; V-set and immunoglobulin domain-containing protein 9 |
Gene ID : | 201633 |
mRNA Refseq : | NM_173799 |
Protein Refseq : | NP_776160 |
MIM : | 612859 |
UniProt ID : | Q495A1 |
Chromosome Location : | 3q13.31 |
Pathway : | Cell adhesion molecules (CAMs) |
Function : | protein binding; receptor binding |
Products Types
◆ Recombinant Protein | ||
TIGIT-1297M | Acitve Recombinant Mouse TIGIT protein(Met1-Gly141), mFc-tagged | +Inquiry |
TIGIT-729H | Recombinant Human TIGIT Protein, IgG2a Fc-tagged | +Inquiry |
TIGIT-726C | Recombinant Cynomolgus monkey TIGIT Protein, Fc-tagged | +Inquiry |
TIGIT-727H | Recombinant Human TIGIT Protein | +Inquiry |
TIGIT-1031H | Recombinant Human TIGIT Protein, DDK/His-tagged | +Inquiry |
◆ Lysates | ||
TIGIT-2610HCL | Recombinant Human TIGIT cell lysate | +Inquiry |
TIGIT-1420MCL | Recombinant Mouse TIGIT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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