Active Recombinant Human Pim-3, His-tagged
Cat.No. : | Pim3-116H |
Product Overview : | Recombinant Human Pim-3 fused with 6His tag at Nterminal, was expressed in Sf21 insect cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis. |
Source : | Sf21 insect cells |
Species : | Human |
Tag : | His |
Form : | 1.05mg/ml of enzyme in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution. |
Bio-activity : | 5210U/mg, where one unit of Pim-3 activity is defined as 1nmol phosphate incorporated into 300µM (RSRHSSYPAGT) per minute at 30°C with a final ATP concentration of 100µM. |
Molecular Mass : | 39.6 kDa |
Storage : | Stable for 6 months at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap. |
Gene Name : | PIM3 pim-3 oncogene [ Homo sapiens (human) ] |
Official Symbol : | PIM3 |
Synonyms : | PIM3; pim-3; pim-3 oncogene; serine/threonine-protein kinase pim-3; serine/threonine kinase Pim-3; EC 2.7.11.1 |
Gene ID : | 415116 |
mRNA Refseq : | NM_001001852 |
Protein Refseq : | NP_001001852 |
MIM : | 610580 |
UniProt ID : | Q86V86 |
Chromosome Location : | 22q13 |
Function : | ATP binding; protein binding; protein serine/threonine kinase activity |
Products Types
◆ Recombinant Protein | ||
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PIM3-0923H | Recombinant Human PIM3 Protein (L2-L326), Tag Free | +Inquiry |
PIM3-4126R | Recombinant Rat PIM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pim3-4870M | Recombinant Mouse Pim3 Protein, Myc/DDK-tagged | +Inquiry |
Pim3-1081H | Recombinant Mouse Pim3 protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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