"PIM3" Related Products

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Recombinant Human Pim-3, His-tagged

Cat.No. : Pim3-116H
Product Overview : Recombinant Human Pim-3 fused with 6­His tag at N­terminal, was expressed in Sf21 insect cells.
Description : The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.
Source : Sf21 insect cells
Species : Human
Tag : His
Form : 1.05mg/ml of enzyme in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution.
Bio-activity : 5210U/mg, where one unit of Pim-3 activity is defined as 1nmol phosphate incorporated into 300µM (RSRHSSYPAGT) per minute at 30°C with a final ATP concentration of 100µM.
Molecular Mass : 39.6 kDa
Storage : Stable for 6 months at -70°C from date of shipment. For maximum recovery of product, centrifuge original vial prior to removing the cap.
Gene Name : PIM3 pim-3 oncogene [ Homo sapiens (human) ]
Official Symbol : PIM3
Synonyms : PIM3; pim-3; pim-3 oncogene; serine/threonine-protein kinase pim-3; serine/threonine kinase Pim-3; EC 2.7.11.1
Gene ID : 415116
mRNA Refseq : NM_001001852
Protein Refseq : NP_001001852
MIM : 610580
UniProt ID : Q86V86
Chromosome Location : 22q13
Function : ATP binding; protein binding; protein serine/threonine kinase activity

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