"MESDC1" Related Products

Recombinant Human MESDC1, His-tagged

Cat.No.: MESDC1-164H
Product Overview: MESDC1, 1-362aa, Human, His tag, E.coli
Description: Mesoderm development candidate 1, also known as MESDC1, belongs to the MESD family. It is a 362 amino acid protein encoded by a gene that maps to human chromosome 15q25.1. MESDC1 acts as a chaperone for low-density lipoprotein receptor (LDLR) proteins in the ER, and particularly associates with Wnt signaling pathway coreceptors LRP5 and LPR6). MESDC1 is required for proper LRP5/6 folding and maturation to the cell surface, which plays a major role in Wnt signaling. Recombinant human MESDC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
Molecular Mass: 40.1 kDa (385aa) confirmed by MALDI-TOF
Protein length: 1-362aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMASGSAG KPTGEAASPA PASAIGGASS QPRKRLVSVC DHCKGKMQLV ADLLLLSSEA RPVLFEGPAS SGAGAESFEQ CRDTIIARTK GLSILTHDVQ SQLNMGRFGE AGDSLVELGD LVVSLTECSA HAAYLAAVAT PGAQPAQPGL VDRYRVTRCR HEVEQGCAVL RATPLADMTP QLLLEVSQGL SRNLKFLTDA CALASDKSRD RFSREQFKLG VKCMSTSASA LLACVREVKV APSELARSRC ALFSGPLVQA VSALVGFATE PQFLGRAAAV SAEGKAVQTA ILGGAMSVVS ACVLLTQCLR DLAQHPDGGA KMSDHRERLR NSACAVSEGC TLLSQALRER SSPRTLPPVN SNSVN
Purity: >95% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)

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