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Recombinant Human PIM2, His-tagged

Cat.No.: PIM2-206H
Product Overview: PIM2, 1-311aa, Human, His tag, E.coli
Description: Serine/threonine-protein kinase pim-2, also known as PIM2, is a serine/threonine protein kinase in the CAMK family. PIM2 is expressed in many tissues, with high levels in spleen, thymus, testis, small intestine, and colon. It is implicated in tumor phenotypes and may be involved in the formation and preservation of Long-Term Potentiation (LTP), a profuse, activity-dependent enhancement of synaptic efficacy that is implicated in long-term memory. Recombinant human PIM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol
Molecular Mass: 36.6 kDa (334aa) confirmed by MALDI-TOF
Protein length: 1-311aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMLTKPLQ GPPAPPGTPT PPPGGKDREA FEAEYRLGPL LGKGGFGTVF AGHRLTDRLQ VAIKVIPRNR VLGWSPLSDS VTCPLEVALL WKVGAGGGHP GVIRLLDWFE TQEGFMLVLE RPLPAQDLFD YITEKGPLGE GPSRCFFGQV VAAIQHCHSR GVVHRDIKDE NILIDLRRGC AKLIDFGSGA LLHDEPYTDF DGTRVYSPPE WISRHQYHAL PATVWSLGIL LYDMVCGDIP FERDQEILEA ELHFPAHVSP DCCALIRRCL APKPSSRPSL EEILLDPWMQ TPAEDVPLNP SKGGPAPLAW SLLP
Purity: >85% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.25 mg/ml (determined by Bradford assay)
Gene Name: PIM2 pim-2 oncogene [ Homo sapiens ]
Official Symbol: PIM2
Synonyms: PIM2; pim-2 oncogene; serine/threonine-protein kinase pim-2; pim-2h; serine/threonine protein kinase pim-2; proto-oncogene Pim-2 (serine threonine kinase);
Gene ID: 11040
mRNA Refseq: NM_006875
Protein Refseq: NP_006866
MIM: 300295
UniProt ID: Q9P1W9
Chromosome Location: Xp11.23
Pathway: Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem;
Function: ATP binding; nucleotide binding; protein serine/threonine kinase activity;

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