Recombinant Human GCHFR, His-tagged
Cat.No. : | GCHFR-245H |
Product Overview : | GCHFR, 1-84aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | GTP cyclohydrolase I feedback regulatory protein(GCHFR) binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. Recombinant human GCHFR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 40% glycerol, 1mM DTT |
Molecular Mass : | 12.1 kDa (107aa) confirmed by MALDI-TOF |
Protein length : | 1-84aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMPYLLIS TQIRMEVGPT MVGDEQSDPE LMQHLGASKR RALGNNFYEY YVDDPPRIVL DKLERRGFRV LSMTGVGQTL VWCLHKE |
Purity : | >95% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | GCHFR GTP cyclohydrolase I feedback regulator [ Homo sapiens ] |
Official Symbol : | GCHFR |
Synonyms : | GCHFR; GTP cyclohydrolase I feedback regulator; GTP cyclohydrolase I feedback regulatory protein; GTP cyclohydrolase 1 feedback regulatory protein; GFRP; HsT16933; P35; MGC138467; MGC138469; |
Gene ID : | 2644 |
mRNA Refseq : | NM_005258 |
Protein Refseq : | NP_005249 |
MIM : | 602437 |
UniProt ID : | P30047 |
Chromosome Location : | 15q15 |
Pathway : | Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem; |
Function : | GTP cyclohydrolase I binding; GTP-dependent protein binding; amino acid binding; enzyme inhibitor activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
GCHFR-1642R | Recombinant Rhesus Macaque GCHFR Protein, His (Fc)-Avi-tagged | +Inquiry |
GCHFR-4796H | Recombinant Human GCHFR Protein, GST-tagged | +Inquiry |
GCHFR-3505M | Recombinant Mouse GCHFR Protein, His (Fc)-Avi-tagged | +Inquiry |
GCHFR-2146R | Recombinant Rat GCHFR Protein, His (Fc)-Avi-tagged | +Inquiry |
GCHFR-1821R | Recombinant Rhesus monkey GCHFR Protein, His-tagged | +Inquiry |
◆ Lysates | ||
GCHFR-692HCL | Recombinant Human GCHFR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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