Active Recombinant Mouse Thbs4, His-tagged

• Cat.No.: Thbs4-120M
• Product Overview: Recombinant Mouse Thbs4 (Gln27-Asn963), fused with a C-terminal 6-His tag, was expressed in CHO Cells.

Specification

• Description: Thrombospondin-4 is a protein that in humans is encoded by the THBS4 gene. The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. Studies of the rat counterpart suggest that this protein may be involved in local signaling in the developing and adult nervous system.
• Source: CHO Cells
• Species: Mouse
• Tag: His
• Predicted N Terminal: Gln27
• Form: Lyophilized from a 0.2 μm filtered solution in PBS.
• Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of SVEC4 10 mouse vascular endothelial cells. The ED50 for this effect is typically 0.1-0.5 μg/mL.
• Molecular Mass: 104.4 kDa
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 200 μg/mL in PBS.

Gene Information

• Gene Name: Thbs4 thrombospondin 4 [ Mus musculus (house mouse) ]
• Official Symbol: Thbs4
• Synonyms: Thbs4; TSP4; thrombospondin 4; thrombospondin-4
• Gene ID: 21828
• mRNA Refseq: NM_011582
• Protein Refseq: NP_035712
• UniProt ID: Q9Z1T2
• Chromosome Location: 13 C3; 13 47.75 cM
• Pathway: ECM-receptor interaction; Focal adhesion; PI3K-Akt signaling pathway; Signal Transduction
• Function: calcium ion binding; collagen binding; fibronectin binding