Recombinant Mouse Thbs4, His-tagged


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Recombinant Mouse Thbs4, His-tagged

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Cat.No. : Thbs4-120M
Product Overview : Recombinant Mouse Thbs4 (Gln27-Asn963), fused with a C-terminal 6-His tag, was expressed in CHO Cells.
Description : Thrombospondin-4 is a protein that in humans is encoded by the THBS4 gene. The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. Studies of the rat counterpart suggest that this protein may be involved in local signaling in the developing and adult nervous system.
Source : CHO Cells
Species : Mouse
Tag : His
Predicted N Terminal : Gln27
Form : Lyophilized from a 0.2 μm filtered solution in PBS.
Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of SVEC4 10 mouse vascular endothelial cells. The ED50 for this effect is typically 0.1-0.5 μg/mL.
Molecular Mass : 104.4 kDa
Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Storage : Avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 200 μg/mL in PBS.
Gene Name : Thbs4 thrombospondin 4 [ Mus musculus (house mouse) ]
Official Symbol : Thbs4
Synonyms : Thbs4; TSP4; thrombospondin 4; thrombospondin-4
Gene ID : 21828
mRNA Refseq : NM_011582
Protein Refseq : NP_035712
UniProt ID : Q9Z1T2
Chromosome Location : 13 C3; 13 47.75 cM
Pathway : ECM-receptor interaction; Focal adhesion; PI3K-Akt signaling pathway; Signal Transduction
Function : calcium ion binding; collagen binding; fibronectin binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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