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Recombinant Human FCGR2A, His-tagged, Biotinylated

Cat.No.: FCGR2A-259H
Product Overview: Human FcGR2A /CD32a Protein, Biotinylated (Biotinylated FcGR2A / CD32a) Gln 34 - Ile 218, was labeled with biotin based on rhCD32a Protein, which was produced in human 293 cells (HEK293).?
Description: This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.?
Source: HEK293
Species: Human
Tag: His
Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose are added as protectants before lyophilization.
Molecular Mass: Biotinylated FcGR2A / CD32a, fused with 6×His tag at the C-terminus, has a calculated MW of 21.3 kDa. The predicted N-terminus is Gln 34. DTT-reduced Protein migrates as 29-32 kDa due to glycosylation.
Endotoxin: Less than 1.0 EU per μg of the Biotinylated FcGR2A / CD32a by the LAL method.
Purity: >95% as determined by reduced SDS-PAGE.
Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C).
Gene Name: FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) [ Homo sapiens ]
Official Symbol: FCGR2A
Synonyms: FCGR2A; Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32) , FCG2, FCGR2, FCGR2A1; low affinity immunoglobulin gamma Fc region receptor II-a; CD32; CD32A; CDw32; IGFR2; Immunoglobulin G Fc receptor II; fcRII-a; fc-gamma-RIIa; fc-gamma RII-a; igG Fc receptor II-a; FCG2; FcGR; FCGR2; FCGR2A1; MGC23887; MGC30032;
Gene ID: 2212
mRNA Refseq: NM_001136219
Protein Refseq: NP_001129691
MIM: 146790
UniProt ID: P12318
Chromosome Location: 1q23
Pathway: Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; Leishmaniasis, organism-specific biosystem; Leishmaniasis, conserved biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; Phagosome, organism-specific biosystem;
Function: IgG binding; receptor activity;

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