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Recombinant Human PTPRF, GST-tagged

Cat.No. : PTPRF-2062H
Product Overview : Recombinant Human PTPRF protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Source : E.coli
Species : Human
Tag : GST
Protein length : 1549-1898aa
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : PTPRF protein tyrosine phosphatase, receptor type, F [ Homo sapiens ]
Official Symbol : PTPRF
Synonyms : PTPRF; protein tyrosine phosphatase, receptor type, F; LAR; receptor-type tyrosine-protein phosphatase F; LCA-homolog; leukocyte common antigen related; leukocyte antigen-related (LAR) PTP receptor; leukocyte antigen-related tyrosine phosphatase; receptor-linked protein-tyrosine phosphatase LAR; protein tyrosine phosphatase, receptor type, F polypeptide; FLJ43335; FLJ45062; FLJ45567;
Gene ID : 5792
mRNA Refseq : NM_002840
Protein Refseq : NP_002831
MIM : 179590
UniProt ID : P10586
Chromosome Location : 1p34
Pathway : Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Insulin Signaling, organism-specific biosystem; Insulin signaling pathway, organism-specific biosystem; Insulin signaling pathway, conserved biosystem;
Function : hydrolase activity; insulin receptor binding; phosphate ion binding; protein tyrosine phosphatase activity; receptor activity; receptor tyrosine kinase binding; transmembrane receptor protein tyrosine phosphatase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Do specific PTPRF inhibitors have therapeutic effects on autoimmune diseases? 11/21/2022

PTPRF inhibitors can inhibit certain abnormal signaling pathways in autoimmune diseases, thereby exerting their role in the treatment of autoimmune diseases.

What is the therapeutic effect of specific PTPRF inhibitors on inflammatory diseases? 10/16/2021

Specific PTPRF inhibitors can inhibit certain signaling pathways in the inflammatory response, thereby playing a role in the treatment of inflammatory diseases.

What is the effect of knocking out the PTPRF gene on tumorigenesis? 10/11/2021

Knocking out the PTPRF gene may increase the risk of developing certain tumors, which may be related to aberrant regulation of cell cycle control and cell growth.

Is there a specific PTPRF inhibitor? 05/17/2021

There are currently some studies that report specific PTPRF inhibitors that can inhibit the enzymatic activity of PTPRF and thus exert therapeutic effects.

Is there a soluble PTPRF protein? 04/22/2021

Yes, soluble PTPRF proteins exist that can be detected in extracellular fluids and may play a role in regulating cell-to-cell communication and signal transduction.

What are the therapeutic strategies for PTPRF protein? 04/22/2020

Therapeutic strategies for PTPRF protein include increasing its expression level, inhibiting its enzymatic activity, and regulating its interaction with other proteins, which can be used to treat PTPRF protein-related diseases.

Customer Reviews (3)

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Reviews
06/11/2022

    Qualitative is very strong, even after a lot of use can still maintain its structural and functional stability, which shows its excellent quality and reliability.

    04/13/2022

      The reproducibility is very good, and I can get consistent results from each experiment, which makes me more confident in the experimental results.

      02/19/2022

        Excellent performance in Western blot, avoiding interference problems in the experiment.

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