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Recombinant Human REV1, His-tagged

Cat.No. : REV1-2257H
Product Overview : Recombinant Human REV1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Source : E.coli
Species : Human
Tag : His
Protein length : C-term-351aa
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : REV1 REV1 homolog (S. cerevisiae) [ Homo sapiens ]
Official Symbol : REV1
Synonyms : REV1; REV1 homolog (S. cerevisiae); REV1 (yeast homolog) like , REV1 like (yeast) , REV1L; DNA repair protein REV1; AIBP80; REV1- like; alpha integrin-binding protein 80; rev1-like terminal deoxycytidyl transferase; REV1L; FLJ21523; MGC26225; MGC163283;
Gene ID : 51455
mRNA Refseq : NM_001037872
Protein Refseq : NP_001032961
MIM : 606134
UniProt ID : Q9UBZ9
Chromosome Location : 2q11.1-q11.2
Pathway : DNA Damage Bypass, organism-specific biosystem; DNA Repair, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Translesion synthesis by DNA polymerases bypassing lesion on DNA tem
Function : DNA-directed DNA polymerase activity; damaged DNA binding; deoxycytidyl transferase activity; magnesium ion binding; protein binding; transferase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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Does REV1 recombinant protein have a role in promoting tumor growth? 09/28/2021

The REV1 recombinant protein may have a growth-promoting effect in some cases, but may have an inhibitory effect in others. The specific mechanism needs to be further studied.

Is the expression level of REV1 recombinant protein affected by cellular stress? 08/20/2021

The expression level of REV1 recombinant protein may be affected by cellular stress, such as DNA damage, but the specific mechanism needs to be further studied.

Is there a potential application for REV1 recombinant protein in drug development? 02/27/2021

As a protein related to DNA damage repair, the enzymatic activity of REV1 recombinant protein may provide a potential target for drug development, but a lot of research is still needed to determine its application prospect.

Is the DNA repair pathway involved in REV1 recombinant protein related to the sensitivity of anticancer drugs? 02/02/2021

Yes, there may be a correlation between the DNA repair pathway involved in the REV1 recombinant protein and the sensitivity of certain anticancer drugs, which warrants further investigation.

Does REV1 recombinant protein have an effect on variation in the human genome? 12/26/2020

The misintroduction of REV1 recombinant protein during DNA damage repair may lead to genomic variation, but the specific mechanism needs to be further studied.

In which experimental models has REV1 recombinant protein been studied? 10/01/2020

REV1 recombinant protein has been extensively studied in cell culture (in vitro) and animal models (in vivo).

Customer Reviews (3)

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Reviews
05/16/2023

    Good solubility and stability in solution.

    08/26/2021

      In special environments, it has good stability.

      05/21/2020

        I have already recommended this brand to my colleagues and friends, and they are all very enthusiastic about this product.

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