"MSLN" Related Products

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Recombinant Human MSLN protein, His-tagged, Biotin Labeled.

Cat.No.: MSLN-10623H
Product Overview: Recombinant Human MSLN(Glu 296 - Gly 580) fused with His tag at C-terminal was expressed in HEK293.
Description: Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
Source: HEK293
Species: Human
Tag : His
Predicted N Terminal: Glu 296
Form: Lyophilized from 0.22µm filtered solution in PBS (pH 7.4) with Trehalose as protectant.
Molecular Mass: The protein has a calculated MW of 33 kDa. The protein migrates as 38-42 kDa on a SDS-PAGE gel under reducing (R) condition due to glycosylation.
Protein length: Glu 296 - Gly 580
Endotoxin: Less than 1.0 EU per μg by the LAL method.
Purity: >95% as determined by SDS-PAGE.
Notes: The primary amines in the side chains of lysine residues and the N-terminus of the protein are conjugated with biotins using standard chemical labeling method. A standard biotin reagent (13.5 angstroms) is used in this product.
Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles.
No activity loss is observed after storage at:
4-8 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
Reconstitution: Reconstitute at 100 μg/mL in sterile deionized water. For best performance, we strongly recommend you to follow the reconstitution protocol provided in the COA.
Gene Name: MSLN mesothelin [ Homo sapiens ]
Official Symbol: MSLN
Synonyms: MSLN; mesothelin; CAK1; MPF; CAK1 antigen; megakaryocyte potentiating factor; soluble MPF mesothelin related protein; pre-pro-megakaryocyte-potentiating factor; SMRP;
Gene ID: 10232
mRNA Refseq: NM_001177355
Protein Refseq: NP_001170826
MIM: 601051
UniProt ID: Q13421
Chromosome Location: 16p13.3

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