"TGFB3" Related Products

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Recombinant human TGFB3, Active

Cat.No.: TGFB3-1571H
Product Overview: Recombinant human TGF-beta3 is a 27.2 kDa protein composed of two identical 118 amino acid polypeptide chains linked by a single disulphide bond.
Description: Recombinant human TGF-beta3 is a 27.2 kDa protein composed of two identical 118 amino acid peptide chains linked by a single disulphide bond. Transforming growth factor–beta is a family of five related cytokines that have been shown on a wide variety of normal and neoplastic cells, indicating the importance of these homo-dimmer proteins as multi-functional regulators of cellular activity. The three mammalian isoforms of TGF-beta (TGF-beta1, TGF-beta2 and TGF-beta3) signal through the same receptor and elicit similar biological responses. They are involved in physiological processes as embryogenesis, tissue remodeling and wound healing.
Source: Human recombinant protein expressed in Nicotiana benthamiana. It is produced by transient expression in non-transgenic plants. This product contains no animal–derived components or impurities. Animal Free product.
Species: Human
Form: Recombinant human TGF beta-3 is lyophilized from a Tris HCl 0.05M buffer at pH 7.4.
Molecular Mass: 27.2 kDa
AA Sequence: HHHHHHALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHSTVLGLYNTLN PEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS
Endotoxin: < 0.04 eu/μg protein (lal>
Purity: >97% by SDS-PAGE gel
Storage: This lyophilized preparation is stable at 2-8o C for short term, long storage it should be kept at -20oC. Reconstituted protein should be stored in working aliquots at –20°C. Repeated freezing and thawing is not recommended.
Reconstitution: Centrifuge vial before opening. Lyophilized protein should be reconstituted in water to a concentration of 25-50 ng/μl. Due to the protein nature, dimmers and multimers may be observed. At higher concentration the solubility may be reduced and multimers generated. Optimal concentration should be determined for specific application and cell lines.
Gene Name: TGFB3 transforming growth factor, beta 3 [ Homo sapiens ]
Official Symbol: TGFB3
Synonyms: TGFB3; transforming growth factor, beta 3; transforming growth factor beta-3; TGF-beta-3; ARVD; TGF-beta3; FLJ16571;
Gene ID: 7043
mRNA Refseq: NM_003239
Protein Refseq: NP_003230
MIM: 190230
UniProt ID: P10600
Chromosome Location: 14q24
Pathway: ALK1 signaling events, organism-specific biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem;
Function: growth factor activity; identical protein binding; protein binding; contributes_to protein binding; protein heterodimerization activity; transforming growth factor beta binding; transforming growth factor beta receptor binding; type I transforming growth

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