Recombinant Human GALNS, GST-tagged
Cat.No. : | GALNS-102H |
Product Overview : | Recombinant Human full-length GALNS (1 a.a. - 522 a.a.), fused with GST-tag at N-terminal, was expressed in wheat germ. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder. |
Source : | Wheat germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 84.4 kDa |
AA Sequence : | MAAVVAATRWWQLLLVLSAAGMGAS GAPQPPNILLLLMDDMGWGDLGVYG EPSRETPNLDRMAAEGLLFPNFYSA NPLCSPSRAALLTGRLPIRNGFYTT NAHARNAYTPQEIVGGIPDSEQLLP ELLKKAGYVSKIVGKWHLGHRPQFH PLKHGFDEWFGSPNCHFGPYDNKAR PNIPVYRDWEMVGRYYEEFPINLKT GEANLTQIYLQEALDFIKRQARHHP FFLYWAVDATHAPVYASKPFLGTSQ RGRYGDAVREIDDSIGKILELLQDL HVADNTFVFFTSDNGAALISAPEQG GSNGPFLCGKQTTFEGGMREPALAW WPGHVTAGQVSHQLGSIMDLFTTSL ALAGLTPPSDRAIDGLNLLPTLLQG RLMDRPIFYYRGDTLMAATLGQHKA HFWTWTNSWENFRQGIDFCPGQNVS GVTTHNLEDHTKLPLIFHLGRDPGE RFPLSFASAEYQEALSRITSVVQQH QEALVPAQPQLNVCNWAVMNWAPPG CEKLGKCLTPPESIPKKCLWSH |
Applications : | ELISA; WB-Re; AP; Array |
Storage : | Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GALNS galactosamine (N-acetyl)-6-sulfate sulfatase [ Homo sapiens (human) ] |
Official Symbol : | GALNS |
Synonyms : | GALNS; GAS; MPS4A; GalN6S; GALNAC6S; galactosamine (N-acetyl)-6-sulfate sulfatase; N-acetylgalactosamine-6-sulfatase; chondroitinase; galNAc6S sulfatase; chondroitinsulfatase; galactose-6-sulfate sulfatase; N-acetylgalactosamine-6-sulfate sulfatase; NP_000503.1; EC 3.1.6.4 |
Gene ID : | 2588 |
mRNA Refseq : | NM_000512 |
Protein Refseq : | NP_000503 |
MIM : | 612222 |
UniProt ID : | P34059 |
Chromosome Location : | 16q24.3 |
Pathway : | Chondroitin sulfate degradation; Keratan sulfate degradation; Lysosome |
Function : | N-acetylgalactosamine-4-sulfatase activity; N-acetylgalactosamine-6-sulfatase activity; metal ion binding |
Products Types
◆ Recombinant Protein | ||
GALNS-3447M | Recombinant Mouse GALNS Protein, His (Fc)-Avi-tagged | +Inquiry |
GALNS-0128H | Recombinant Human GALNS Protein (M1-H522), Tag Free | +Inquiry |
GALNS-2120R | Recombinant Rat GALNS Protein, His (Fc)-Avi-tagged | +Inquiry |
Galns-3140M | Recombinant Mouse Galns Protein, Myc/DDK-tagged | +Inquiry |
GALNS-0129H | Recombinant Human GALNS Protein (M1-H522), His tagged | +Inquiry |
◆ Lysates | ||
GALNS-6040HCL | Recombinant Human GALNS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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