Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human TNKS, GST-tagged

Cat.No. : TNKS-3327H
Product Overview : Recombinant Human TNKS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-329aa
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase [ Homo sapiens ]
Official Symbol : TNKS
Synonyms : TNKS; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; tankyrase-1; PARP 5a; PARP5A; pART5; TIN1; TINF1; TNKS1; TANK1; TNKS-1; tankyrase I; poly [ADP-ribose] polymerase 5A; TRF1-interacting ankyrin-related ADP-ribose polymerase; PARPL; PARP-5a;
Gene ID : 8658
mRNA Refseq : NM_003747
Protein Refseq : NP_003738
MIM : 603303
UniProt ID : O95271
Chromosome Location : 8p23.1
Pathway : Regulation of Telomerase, organism-specific biosystem;
Function : NAD+ ADP-ribosyltransferase activity; metal ion binding; protein binding; transferase activity, transferring glycosyl groups; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (5)

Ask a question
What are the potential side effects of targeting TNKS protein in cancer therapy? 08/29/2021

Potential side effects may include gastrointestinal toxicity, hematologic toxicity, and adverse effects on the bone marrow.

How is TNKS protein related to telomere maintenance? 08/21/2021

TNKS protein is involved in the PARP-mediated regulation of telomere length and stability.

How does TNKS protein affect DNA repair mechanisms? 06/29/2021

TNKS protein plays a role in regulating the DNA damage response and repair mechanisms in cells.

Are there any specific inhibitors targeting TNKS protein in clinical use? 01/05/2021

Several inhibitors targeting TNKS protein, such as tankyrase inhibitors, are being evaluated in clinical trials.

Are there any genetic mutations associated with TNKS protein that predispose individuals to certain cancers? 04/19/2017

Mutations in the TNKS gene have been implicated in colorectal cancer and other malignancies.

Customer Reviews (3)

Write a review
Reviews
02/13/2023

    One of the key advantages of working with the TNKS protein is the comprehensive support provided by its manufacturer.

    09/20/2021

      This information is crucial for researchers in understanding the protein's behavior and interaction within their specific experimental context.

      12/11/2020

        TNKS is known for its high purity and quality, ensuring accurate and reproducible results.

        Ask a Question for All TNKS Products

        Required fields are marked with *

        My Review for All TNKS Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends