Recombinant Human TNKS, GST-tagged
Cat.No. : | TNKS-3327H |
Product Overview : | Recombinant Human TNKS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-329aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase [ Homo sapiens ] |
Official Symbol : | TNKS |
Synonyms : | TNKS; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase; tankyrase-1; PARP 5a; PARP5A; pART5; TIN1; TINF1; TNKS1; TANK1; TNKS-1; tankyrase I; poly [ADP-ribose] polymerase 5A; TRF1-interacting ankyrin-related ADP-ribose polymerase; PARPL; PARP-5a; |
Gene ID : | 8658 |
mRNA Refseq : | NM_003747 |
Protein Refseq : | NP_003738 |
MIM : | 603303 |
UniProt ID : | O95271 |
Chromosome Location : | 8p23.1 |
Pathway : | Regulation of Telomerase, organism-specific biosystem; |
Function : | NAD+ ADP-ribosyltransferase activity; metal ion binding; protein binding; transferase activity, transferring glycosyl groups; zinc ion binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionPotential side effects may include gastrointestinal toxicity, hematologic toxicity, and adverse effects on the bone marrow.
TNKS protein is involved in the PARP-mediated regulation of telomere length and stability.
TNKS protein plays a role in regulating the DNA damage response and repair mechanisms in cells.
Several inhibitors targeting TNKS protein, such as tankyrase inhibitors, are being evaluated in clinical trials.
Mutations in the TNKS gene have been implicated in colorectal cancer and other malignancies.
Customer Reviews (3)
Write a reviewOne of the key advantages of working with the TNKS protein is the comprehensive support provided by its manufacturer.
This information is crucial for researchers in understanding the protein's behavior and interaction within their specific experimental context.
TNKS is known for its high purity and quality, ensuring accurate and reproducible results.
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