Recombinant Human UPF1, GST-tagged

• Cat.No.: UPF1-3603H
• Product Overview: Recombinant Human UPF1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-350aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) [ Homo sapiens ]
• Official Symbol: UPF1
• Synonyms: UPF1; UPF1 regulator of nonsense transcripts homolog (yeast); regulator of nonsense transcripts 1 , RENT1; regulator of nonsense transcripts 1; HUPF1; KIAA0221; NORF1; pNORF1; smg 2; smg 2 homolog; nonsense mediated mRNA decay factor (C. elegans); UP Frameshift 1; delta helicase; yeast Upf1p homolog; ATP-dependent helicase RENT1; nonsense mRNA reducing factor 1; up-frameshift mutation 1 homolog; up-frameshift suppressor 1 homolog; smg-2 homolog, nonsense mediated mRNA decay factor; RENT1; smg-2; FLJ43809; FLJ46894
• Gene ID: 5976
• mRNA Refseq: NM_002911
• Protein Refseq: NP_002902
• MIM: 601430
• UniProt ID: Q92900
• Chromosome Location: 19p13.2-p13.11
• Pathway: Exon junction complex (EJC), organism-specific biosystem; Gene Expression, organism-specific biosystem; Nonsense Mediated Decay Enhanced by the Exon Junction Complex, organism-specific biosystem; Nonsense Mediated Decay Independent of the Exon Junction Co
• Function: ATP binding; ATP-dependent RNA helicase activity; DNA binding; RNA binding; chromatin binding; helicase activity; hydrolase activity; metal ion binding; nucleotide binding; protein binding; zinc ion binding