Gene Name |
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast) [ Homo sapiens ] |
Official Symbol |
UPF1 |
Synonyms |
UPF1; UPF1 regulator of nonsense transcripts homolog (yeast); regulator of nonsense transcripts 1 , RENT1; regulator of nonsense transcripts 1; HUPF1; KIAA0221; NORF1; pNORF1; smg 2; smg 2 homolog; nonsense mediated mRNA decay factor (C. elegans); UP Frameshift 1; delta helicase; yeast Upf1p homolog; ATP-dependent helicase RENT1; nonsense mRNA reducing factor 1; up-frameshift mutation 1 homolog; up-frameshift suppressor 1 homolog; smg-2 homolog, nonsense mediated mRNA decay factor; RENT1; smg-2; FLJ43809; FLJ46894; |
Gene ID |
5976 |
mRNA Refseq |
NM_002911 |
Protein Refseq |
NP_002902 |
MIM |
601430 |
UniProt ID |
Q92900 |
Chromosome Location |
19p13.2-p13.11 |
Pathway |
Exon junction complex (EJC), organism-specific biosystem; Gene Expression, organism-specific biosystem; Nonsense Mediated Decay Enhanced by the Exon Junction Complex, organism-specific biosystem; Nonsense Mediated Decay Independent of the Exon Junction Co |
Function |
ATP binding; ATP-dependent RNA helicase activity; DNA binding; RNA binding; chromatin binding; helicase activity; hydrolase activity; metal ion binding; nucleotide binding; protein binding; zinc ion binding; |