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Recombinant Human TSHR

Cat.No. : TSHR-3451H
Product Overview : Recombinant human TSHR (66 kDa) protein was expressed in E. coli with His-tag.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a membrane protein and a major controller of thyroid cellmetabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity ismediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : His
Form : Each vial contains Tris-HCl (pH7.4 ± 0.2), with 0.02% NaN3.
Molecular Mass : 66 kDa
AA Sequence : GMGCSSPPCECHQEEDFRVTCKDIQ RIPSLPPSTQTLKLIETHLRTIPSH AFSNLPNISRIYVSIDVTLQQLESH SFYNLSKVTHIEIRNTRNLTYIDPD ALKELPLLKFLGIFNTGLKMFPDLT KVYSTDIFFILEITDNPYMTSIPVN AFQGLCNETLTLKLYNNGFTSVQGY AFNGTKLDAVYLNKNKYLTVIDKDA FGGVYSGPSLLDVSQTSVTALPSKG LEHLKELIARNTWTLKKLPLSLSFL HLTRADLSYPSHCCAFKNQKKIRGI LESLMCNESSMQSLRQRKSVNALNS PLHQEYEENLGDSIVGYKEKSKFQD THNNAHYYVFFEEQEDEIIGFGQEL KNPQEETLQAFDSHYDYTICGDSED MVCTPKSDEFNPCEDIMGYKFLRIV VWFVSLLALLGNVFVLLILLTSHYK LNVPRFLMCNLAFADFCMGMYLLLI ASVDLYTHSEYYNHAIDWQTGPGCN TAGFFTVFASELSVYTLTVITLERW YAITFAMRLDRKIRLRHACAIMVGG WVCCFLLALLPLVGISSYAKVSICL PMDTETPLALAYIVFVLTLNIVAFV IVCCCYVKIYITVRNPQYNPGDKDT KIAKRMAVLIFTDFICMAPISFYAL SAILNKPLITVSNSKILLVLFYPLN SCANPFLYAIFTKAFQRDVFILLSK FGICKRQAQAYRGQRVPPKNSTDIQ VQKVTHEMRQGLHNMEDVYELIENS HLTPKKQGQISEEYMQTVL
Purity : > 90%
Applications : ELISA, SDS-PAGE
Storage : Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Gene Name : TSHR thyroid stimulating hormone receptor [ Homo sapiens (human) ]
Official Symbol : TSHR
Synonyms : TSHR; LGR3; CHNG1; hTSHR-I; thyroid stimulating hormone receptor; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2
Gene ID : 7253
mRNA Refseq : NM_000369
Protein Refseq : NP_000360
MIM : 603372
UniProt ID : P16473

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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