Recombinant Human TSHR TSHR-3451H

Recombinant Human TSHR

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Recombinant Human TSHR

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Cat.No. : TSHR-3451H
Product Overview : Recombinant human TSHR (66 kDa) protein was expressed in E. coli with His-tag.
Description : The protein encoded by this gene is a membrane protein and a major controller of thyroid cellmetabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity ismediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Source : E. coli
Species : Human
Tag : His
Form : Each vial contains Tris-HCl (pH7.4 ± 0.2), with 0.02% NaN3.
Molecular Mass : 66 kDa
AA Sequence : GMGCSSPPCECHQEE DFRVTCKDIQRIPSL PPSTQTLKLIETHLR TIPSHAFSNLPNISR IYVSIDVTLQQLESH SFYNLSKVTHIEIRN TRNLTYIDPDALKEL PLLKFLGIFNTGLKM FPDLTKVYSTDIFFI LEITDNPYMTSIPVN AFQGLCNETLTLKLY NNGFTSVQGYAFNGT KLDAVYLNKNKYLTV IDKDAFGGVYSGPSL LDVSQTSVTALPSKG LEHLKELIARNTWTL KKLPLSLSFLHLTRA DLSYPSHCCAFKNQK KIRGILESLMCNESS MQSLRQRKSVNALNS PLHQEYEENLGDSIV GYKEKSKFQDTHNNA HYYVFFEEQEDEIIG FGQELKNPQEETLQA FDSHYDYTICGDSED MVCTPKSDEFNPCED IMGYKFLRIVVWFVS LLALLGNVFVLLILL TSHYKLNVPRFLMCN LAFADFCMGMYLLLI ASVDLYTHSEYYNHA IDWQTGPGCNTAGFF TVFASELSVYTLTVI TLERWYAITFAMRLD RKIRLRHACAIMVGG WVCCFLLALLPLVGI SSYAKVSICLPMDTE TPLALAYIVFVLTLN IVAFVIVCCCYVKIY ITVRNPQYNPGDKDT KIAKRMAVLIFTDFI CMAPISFYALSAILN KPLITVSNSKILLVL FYPLNSCANPFLYAI FTKAFQRDVFILLSK FGICKRQAQAYRGQR VPPKNSTDIQVQKVT HEMRQGLHNMEDVYE LIENSHLTPKKQGQI SEEYMQTVL
Purity : > 90%
Applications : ELISA, SDS-PAGE
Storage : Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Gene Name : TSHR thyroid stimulating hormone receptor [ Homo sapiens (human) ]
Official Symbol : TSHR
Synonyms : TSHR; LGR3; CHNG1; hTSHR-I; thyroid stimulating hormone receptor; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; seven transmembrane helix receptor; thyroid stimulating hormone receptor, isoform 2
Gene ID : 7253
mRNA Refseq : NM_000369
Protein Refseq : NP_000360
MIM : 603372
UniProt ID : P16473

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