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Recombinant Human AGXT, MYC/DDK-tagged

Cat.No.: AGXT-84837H
Product Overview: Recombinant Human AGXT, fused with C-terminal MYC/DDK, was expressed in HEK293.
Description: This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria.
Source: HEK293
Species: Human
Tag: MYC/DDK
Molecular Mass: 42.8 kDa
Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration: >50 ug/mL as determined by microplate BCA method
Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name: AGXT alanine-glyoxylate aminotransferase [ Homo sapiens (human) ]
Official Symbol: AGXT
Synonyms: AGXT; AGT; PH1; SPT; AGT1; SPAT; TLH6; AGXT1; alanine-glyoxylate aminotransferase; serine--pyruvate aminotransferase; serine-pyruvate aminotransferase; serine:pyruvate aminotransferase; alanine--glyoxylate aminotransferase; L-alanine: glyoxylate aminotransferase 1; hepatic peroxisomal alanine:glyoxylate aminotransferase; NP_000021.1; EC 2.6.1.44; EC 2.6.1.51
Gene ID: 189
mRNA Refseq: NM_000030
Protein Refseq: NP_000021
MIM: 604285
UniProt ID: P21549
Chromosome Location: 2q37.3
Pathway: Alanine and aspartate metabolism; Carbon metabolism; Glyoxylate and dicarboxylate metabolism
Function: alanine-glyoxylate transaminase activity; protein homodimerization activity; pyridoxal phosphate binding

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