Active Recombinant Mouse Dsg2, Fc-tagged

• Cat.No.: Dsg2-41M
• Product Overview: Recombinant Mouse Dsg2 was expressed in Mouse NSO Cells.

Specification

• Species: Mouse
• Source: Mammalian Cells
• Tag: Fc
• Description: Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene.
• Predicted N Terminal: Leu29 & Ala55
• Form: Lyophilized from a 0.2 μm filtered solution in PBS.
• Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of BUD?8 human fibroblast cells.When 3 x 10^4 cells are added to Recombinant Mouse Desmoglein?2 Fc Chimera coated plates (10 μg/mL, 100 μL/well), approximately 30%?60% will adhere after 1 hour at 37 °C.Optimal dilutions should be determinded by each laboratory for each application.
• Molecular Mass: Predicted Molecular Mass: 92.9 kDa (monomer)SDS-PAGE: 100-120 kDa, reducing conditions
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 °C as supplied.1 month, 2 to 8 °C under sterile conditions after reconstitution.3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 400 μg/mL in PBS.

Gene Information

• Gene Name: Dsg2 desmoglein 2 [ Mus musculus (house mouse) ]
• Official Symbol: Dsg2
• Synonyms: Dsg2; AA408168; D18Ertd293e; desmoglein 2; desmoglein-2
• Gene ID: 13511
• mRNA Refseq: NM_007883
• Protein Refseq: NP_031909
• UniProt ID: O55111
• Chromosome Location: 18 A2; 18 11.42 cM
• Pathway: Apoptosis; Apoptotic cleavage of cell adhesion proteins; Apoptotic execution phase
• Function: calcium ion binding; metal ion binding