"SPINK1" Related Products

Recombinant Human serine peptidase inhibitor, Kazal type 1, His-tagged

Cat.No.: SPINK1-243H
Product Overview: SPINK1, 24-79aa, Human, His tag, E.coli
Description: SPINK1 is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. Recombinant human SPINK1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Source: E.coli
Species: Human
Tag: His-tag
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Molecular Mass: 8.6 kDa (79aa), confirmed by MALDI-TOF
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSDSLGREA KCYNELNGCT KIYDPVCGTD GNTYPNECVL CFENRKRQTS ILIQKSGPC
Purity: >90% by SDS - PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)
Gene Name: SPINK1 serine peptidase inhibitor, Kazal type 1 [ Homo sapiens ]
Official Symbol: SPINK1
Synonyms: SPINK1; serine peptidase inhibitor, Kazal type 1; serine protease inhibitor, Kazal type 1; pancreatic secretory trypsin inhibitor; PCTT; PSTI; Spink3; TATI; tumor-associated trypsin inhibitor; serine protease inhibitor Kazal-type 1; TCP;
Gene ID: 6690
mRNA Refseq: NM_003122
Protein Refseq: NP_003113
MIM: 167790
UniProt ID: P00995
Chromosome Location: 5q32
Function: endopeptidase inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity;

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