Recombinant Human Lck interacting transmembrane adaptor 1, His-tagged
Cat.No. : | LIME1-323H |
Product Overview : | LIME1, 28-295aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | Lck-interacting transmembrane adapter 1 precursor, also known as LIME1, was previously characterized as a transmembrane adaptor protein mediating TCR-dependent T cell activation. LIME1 becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 coreceptors. Phospho-LIME1 associates with the Src family kinase Lck and its negative regulator, Csk. Recombinant human LIME1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.4M Urea |
Molecular Mass : | 30.8 kDa (291aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSCTACRRP EDAVAPRKRA RRQRARLQGS ATAAEASLLR RTHLCSLSKS DTRLHELHRG PRSSRALRPA SMDLLRPHWL EVSRDITGPQ AAPSAFPHQE LPRALPAAAA TAGCAGLEAT YSNVGLAALP GVSLAASPVV AEYARVQKRK GTHRSPQEPQ QGKTEVTPAA QVDVLYSRVC KPKRRDPGPT TDPLDPKGQG AILALAGDLA YQTLPLRALD VDSGPLENVY ESIRELGDPA GRSSTCGAGT PPASSCPSLG RGWRPLPASL P |
Purity : | >80% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by Bradford assay) |
Gene Name : | LIME1 Lck interacting transmembrane adaptor 1 [ Homo sapiens ] |
Official Symbol : | LIME1 |
Synonyms : | LIME1; Lck interacting transmembrane adaptor 1; lck-interacting transmembrane adapter 1; dJ583P15.4; FLJ20406; LIME; lck-interacting molecule; lck-interacting membrane protein; LP8067; RP4-583P15.5; |
Gene ID : | 54923 |
mRNA Refseq : | NM_017806 |
Protein Refseq : | NP_060276 |
MIM : | 609809 |
UniProt ID : | Q9H400 |
Chromosome Location : | 20q13.33 |
Pathway : | B Cell Receptor Signaling Pathway, organism-specific biosystem; T Cell Receptor Signaling Pathway, organism-specific biosystem; |
Function : | growth factor receptor binding; protein kinase binding; |
Products Types
◆ Recombinant Protein | ||
LIME1-3361H | Recombinant Human LIME1 Protein, His (Fc)-Avi-tagged | +Inquiry |
LIME1-957H | Recombinant Human LIME1 | +Inquiry |
◆ Lysates | ||
LIME1-4740HCL | Recombinant Human LIME1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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