Recombinant Human homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1, His-tagged

• Cat.No.: HERPUD1-628H
• Product Overview: HERPUD1, 1-263a Human, His tag, E.coli

Specification

• Description: Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, also known as HERPUD1, is a 391 amino acid multi-pass membrane protein that localizes to the ER and contains one N-terminal ubiquitin-like domain. Widely expressed with highest expression in the brain, HERP is a component of the ERAD system and, via its ubiquitin-like domain, is thought to be involved in the destruction of misfolded proteins. Recombinant human HERPUD1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
• Source: E.coli
• Species: Human
• Tag: His-tag
• Form: Liquid. In Phosphate buffer saline (pH 7.4) containing 10% glycerol
• Molecular Mass: 31.6 kDa (286aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMESETEP EPVTLLVKSP NQRHRDLELS GDRGWSVGHL KAHLSRVYPE RPRPEDQRLI YSGKLLLDHQ CLRDLLPKQE KRHVLHLVCN VKSPSKMPEI NAKVAESTEE PAGSNRGQYP EDSSSDGLRQ REVLRNLSSP GWENISRPEA AQQAFQGLGP GFSGYTPYGW LQLSWFQQIY ARQYYMQYLA ATAASGAFVP PPSAQEIPVV SAPAPAPIHN QFPAENQPAN QNAAPQVVVN PGANQNLRMN AQGGPIVEED DEINRD
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 [ Homo sapiens ]
• Official Symbol: HERPUD1
• Synonyms: HERPUD1; homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; HERP; KIAA0025; Mif1; SUP; MMS-inducible; methyl methanesulfonate (MMF)-inducible fragment protein 1; homocysteine-inducible endoplasmic reticulum stress-inducible ubiquitin-like domain member 1 protein
• Gene ID: 9709
• mRNA Refseq: NM_001010989
• Protein Refseq: NP_001010989
• MIM: 608070
• UniProt ID: Q15011
• Chromosome Location: 16q13
• Pathway: Activation of Genes by ATF4, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Diurnally regulated genes with circadian orthologs, organism-specific biosystem; HRD1/SEL1 ERAD complex, organism-specific biosystem; HRD1/SEL1 ERAD complex, conserved biosystem; PERK regulated gene expression, organism-specific biosystem
• Function: molecular_function