Recombinant Human CCL4, His-tagged

• Cat.No.: CCL4-247H
• Product Overview: A DNA sequence encoding human CCL4 (NP_002975.1) (Ala24-Gln92) was expressed with a polyhistidine tag at the C-terminus.

Specification

• Source: Yeast
• Species: Human
• Tag: His
• Form: Lyophilized from sterile PBS, pH7.4.
• Molecular Mass: The recombinant human CCL4 consists of 79 amino acids and predicts a molecular mass of 9.2 KDa. It migrates as an approximately 12-16 KDa band in SDS-PAGE under reducing conditions.
• Protein length: Ala24-Gln92
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >90 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: CCL4 chemokine (C-C motif) ligand 4 [ Homo sapiens ]
• Official Symbol: CCL4
• Synonyms: CCL4; chemokine (C-C motif) ligand 4; LAG1, SCYA4, small inducible cytokine A4 (homologous to mouse Mip 1b); C-C motif chemokine 4; Act 2; AT744.1; MIP 1 beta; PAT 744; SIS-gamma; MIP-1-beta(1-69); CC chemokine ligand 4; secreted protein G-26; T-cell activation protein 2; small-inducible cytokine A4; lymphocyte-activation gene 1; G-26 T-lymphocyte-secreted protein; lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; small inducible cytokine A4 (homologous to mouse Mip-1b); ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; MIP-1-beta; MGC104418; MGC126025; MGC126026
• Gene ID: 6351
• mRNA Refseq: NM_002984
• Protein Refseq: NP_002975
• MIM: 182284
• UniProt ID: P13236
• Chromosome Location: 17q21-q23
• Pathway: Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem
• Function: CCR1 chemokine receptor binding; CCR5 chemokine receptor binding; chemokine activity; cytokine activity