"LSM1" Related Products


Recombinant Human LSM1, His-tagged

Cat.No.: LSM1-331H
Product Overview: A DNA sequence encoding the mature form of human LSM1 (O15116) (Met1-Tyr133) was expressed with a polyhistide tag at the N-terminus.
Description: LSM1 is a Sm-like protein. Sm-like proteins include the Sm sequence motif, which consists of two regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. Sm-like proteins can be detected in a variety of organisms based on sequence homology with the Sm protein family. LSM1 facilitates RNA protein interactions and structural modifications which are required during ribosomal subunit assembly. LSM1 also plays a role in replication-dependent histone mRNA degradation and binds specifically to the 3""-terminal U-tract of U6 snRNA.
Source: E. coli
Species: Human
Tag: His
Form: Lyophilized from sterile PBS, pH7.4.
Molecular Mass: The recombinant human LSM1 consists of 148 amino acids and predicts a molecular mass of 17 KDa. It migrates as an approximately 19-21 KDa band in SDS-PAGE under reducing conditions.
Protein length: Met1-Tyr133
Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
Purity: >85 % as determined by SDS-PAGE
Stability: Samples are stable for up to twelve months from date of receipt at -70℃
Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.
Gene Name: LSM1 LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae) [ Homo sapiens ]
Official Symbol: LSM1
Synonyms: LSM1; LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); U6 snRNA-associated Sm-like protein LSm1; CASM; YJL124C; small nuclear ribonuclear CaSm; cancer-associated Sm-like protein;
Gene ID: 27257
mRNA Refseq: NM_014462
Protein Refseq: NP_055277
MIM: 607281
UniProt ID: O15116
Chromosome Location: 8p11.2
Pathway: Deadenylation-dependent mRNA decay, organism-specific biosystem; Gene Expression, organism-specific biosystem; Lsm 1-7 complex, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem; mRNA Decay by 5 to 3 Exoribonuclease, organism-specific biosystem;
Function: RNA binding; protein binding;

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