Recombinant Rat Il23a&Il12b
Cat.No. : | Il23a&Il12b-556R |
Product Overview : | A DNA sequence encoding the rat IL23A (NP_569094.1) (Met1-Ala196) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the rat IL12B (EDM04146.1) (Met1-Ser335) was expressed with a polyhistidine tag at t |
- Specification
- Gene Information
- Related Products
Source : | Human Cells |
Species : | Rat |
Form : | Lyophilized from sterile PBS, pH7.4. |
Molecular Mass : | The recombinant rat IL23A & the rat IL12B comprises 510 (186+324) amino acids and has a calculated molecular mass of 58.2 (21+37.2) KDa. The apparent molecular mass of the rat IL23A & the rat IL12B heterodimer is approximately 47.08, 43.29, 27.67 and 24.75 KDa respectively in SDS-PAGE. |
Protein length : | Met1-Ala196 & Met1-Ser335 |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | (17.9+53.5+2.9+23.8) % as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70℃ |
Storage : | Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | Hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | Il23a Interleukin 23, alpha subunit p19 [ Rattus norvegicus (Norway rat) ] |
Official Symbol : | Il23a&Il12b |
Synonyms : | Il23a; Interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin-23 subunit p19 |
Gene ID : | 155140 |
mRNA Refseq : | NM_130410 |
Protein Refseq : | NP_569094 |
UniProt ID : | Q91Z84 |
Chromosome Location : | 7q11 |
Pathway : | Cytokine-cytokine receptor interaction; Inflammatory bowel disease (IBD); Rheumatoid arthritis |
Function : | cytokine activity; interleukin-23 receptor binding; contributes_to interleukin-23 receptor binding |
Products Types
◆ Recombinant Protein | ||
IL23A-02H | Recombinant Human Active IL23A Protein, His-tagged | +Inquiry |
IL23A-451H | Recombinant Human IL23A Protein, Fc-tagged | +Inquiry |
Il23A-23H | Recombinant Human Il23A&IL12B Protein, His-tagged | +Inquiry |
Il23a-3516M | Recombinant Mouse Il23a Protein, Myc/DDK-tagged | +Inquiry |
IL23A-01H | Active Recombinant Human IL23A Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
IL23A-5231HCL | Recombinant Human IL23A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionPlease inquiry our product manager with specific product.
Yes, drugs like ustekinumab and risankizumab, which target IL23A, have been approved for certain autoimmune diseases.
IL23A primarily plays a role in regulating the adaptive immune response.
IL23A is associated with the inflammation of the spine and joints seen in ankylosing spondylitis, making it a target for therapeutic intervention.
In rheumatoid arthritis, IL23A is involved in the dysregulation of the immune system, leading to joint inflammation and damage.
IL23A is implicated in the pathogenesis of Crohn's disease, contributing to chronic inflammation in the gastrointestinal tract.
Customer Reviews (3)
Write a reviewCoupled with the manufacturer's exceptional technical support and commitment to customer satisfaction, researchers can confidently utilize the IL23A protein in their studies, knowing that they have the necessary resources and assistance to succeed.
Its remarkable attributes and consistent results make it an indispensable tool in various experimental applications.
Highly recommended for its exceptional performance in ELISA, the IL23A protein is a top contender for researchers involved in protein electron microscopy structure analysis.
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