Recombinant Human TPM3, His-tagged
Cat.No. : | TPM3-55H |
Product Overview : | Full-length recombinant human TPM3 protein was expressed in E.coli cells using an N-terminal His tag. |
- Specification
- Gene Information
- Related Products
Description : | TPM3 or tropomyosin 3 is a member of the tropomyosin family of actin-binding proteins that are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. TPM3 involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. TPM3 protein is substituted for the external domain of a putative tyrosine-kinase cell surface receptor to create the TRK oncogene. TPM3 are a common cause of congenital fiber type disproportion. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. |
Molecular Mass : | ~39 kDa |
Applications : | Western Blot |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | TPM3 tropomyosin 3 [ Homo sapiens ] |
Official Symbol : | TPM3 |
Synonyms : | TPM3; tropomyosin 3; NEM1; tropomyosin alpha-3 chain; TRK; tropomyosin-3; tropomyosin-5; gamma-tropomyosin; tropomyosin gamma; cytoskeletal tropomyosin TM30; heat-stable cytoskeletal protein 30 kDa; TM3; TM5; CFTD; TM-5; TM30; hTM5; TM30nm; TPMsk3; hscp30; OK/SW-cl.5; MGC3261; FLJ41118; MGC14582; MGC72094; |
Gene ID : | 7170 |
mRNA Refseq : | NM_001043351 |
Protein Refseq : | NP_001036816 |
MIM : | 191030 |
UniProt ID : | P06753 |
Chromosome Location : | 1q21.2 |
Pathway : | Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; Hypertrophic cardiomyopathy (HCM), conserved biosystem; Muscle contraction, organism-specific biosystem; |
Function : | actin binding; molecular_function; |
Products Types
◆ Recombinant Protein | ||
TPM3-5900R | Recombinant Rat TPM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
TPM3-9538M | Recombinant Mouse TPM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
TPM3-4733R | Recombinant Rhesus Macaque TPM3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Tpm3-6600M | Recombinant Mouse Tpm3 Protein, Myc/DDK-tagged | +Inquiry |
TPM3-0145H | Recombinant Human TPM3 Protein (M2-I285), His/GST tagged | +Inquiry |
◆ Lysates | ||
TPM3-842HCL | Recombinant Human TPM3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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