Recombinant Mouse Ascl2, His-tagged
Cat.No. : | Ascl2-3065M |
Product Overview : | Achaete-scute homolog 2 (Ascl2) |
- Specification
- Gene Information
- Related Products
Source : | E. Coli or Yeast |
Species : | Mouse |
Tag : | His |
Form : | This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications. |
Protein length : | 263 |
Purity : | >90% |
Notes : | Small volumes of Ascl2 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | Store at -20 degree C. For extended storage, store at -20 or -80 degree C. |
Storage Buffer : | PBS pH 7.4, 50% glycerol |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name : | Ascl2 achaete-scute complex homolog 2 (Drosophila) [ Mus musculus ] |
Official Symbol : | Ascl2 |
Synonyms : | ASCL2; achaete-scute complex homolog 2 (Drosophila); achaete-scute homolog 2; ASH-2; mASH-2; mammalian achaete scute homolog 2; achaete-scute complex homolog-like 2; long transient receptor potential-related channel 5; Mash2; bHLHa45; 2410083I15Rik; |
Gene ID : | 17173 |
mRNA Refseq : | NM_008554 |
Protein Refseq : | NP_032580 |
Function : | DNA binding; E-box binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; |
Products Types
◆ Recombinant Protein | ||
Ascl2-1740M | Recombinant Mouse Ascl2 Protein, Myc/DDK-tagged | +Inquiry |
ASCL2-387H | Recombinant Human ASCL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ASCL2-2532M | Recombinant Mouse ASCL2 Protein (1-263 aa), His-Myc-tagged | +Inquiry |
ASCL2-785M | Recombinant Mouse ASCL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ASCL2-475R | Recombinant Rat ASCL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionASCL2, along with other transcription factors and signaling molecules, has been used in combination to induce cellular reprogramming and pluripotency in certain contexts, demonstrating its ability to alter cell fate.
ASCL2's primary role is in the gastrointestinal tract, but it may also have roles in other tissues and organs during development, including lung and pancreas.
ASCL2 interacts with various co-factors and proteins involved in stem cell regulation and development, including β-catenin, POU5F1 (Oct4), and SMAD proteins.
Yes, ASCL2 is crucial for the normal development of the gastrointestinal tract, particularly in regulating the differentiation and proliferation of intestinal stem cells.
ASCL2 is being explored as a potential therapeutic target for colorectal cancer due to its involvement in promoting abnormal cell proliferation. Targeting ASCL2 may help inhibit tumor growth and progression.
ASCL2 promotes the self-renewal of intestinal stem cells by activating specific gene expression programs involved in stem cell maintenance. It also regulates the balance between proliferation and differentiation of these cells.
Customer Reviews (3)
Write a reviewThe manufacturer's commitment to providing excellent technical support is highly valuable.
The combination of high-quality ASCL2 protein and excellent technical support provided by the manufacturer makes them the ideal choice for my research.
The ASCL2 protein offered by the manufacturer is of exceptional quality, and it meets the rigorous standards necessary for my experimental needs.
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