Recombinant Human ADH4, His-tagged

• Cat.No.: ADH4-3252H
• Product Overview: Alcohol dehydrogenase 4 (ADH4)

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 380
• Description: This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of ADH4 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide [ Homo sapiens ]
• Official Symbol: ADH4
• Synonyms: ADH4; alcohol dehydrogenase 4 (class II), pi polypeptide; alcohol dehydrogenase 4; ADH 2; aldehyde reductase; alcohol dehydrogenase class II pi chain; ADH-2
• Gene ID: 127
• mRNA Refseq: NM_000670
• Protein Refseq: NP_000661
• MIM: 103740
• UniProt ID: P08319
• Chromosome Location: 4q22
• Pathway: Biological oxidations, organism-specific biosystem; Drug metabolism - cytochrome P450, organism-specific biosystem; Drug metabolism - cytochrome P450, conserved biosystem; Ethanol oxidation, organism-specific biosystem; Fatty Acid Omega Oxidation, organis
• Function: NAD binding; NADPH:quinone reductase activity; alcohol dehydrogenase (NAD) activity; alcohol dehydrogenase activity, zinc-dependent; alditol:NADP+ 1-oxidoreductase activity; all-trans retinal binding; benzaldehyde dehydrogenase activity; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; retinol binding; retinol dehydrogenase activity; zinc ion binding