Recombinant Human ApoE3
| Cat.No. : | ApoE3-3562H |
| Product Overview : | ApoE3 |
- Specification
- Gene Information
- Related Products
| Description : | Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. |
| Source : | E. Coli |
| Species : | Human |
| Form : | Lyophilized |
| Molecular Mass : | 36,154 Da |
| Protein length : | 317 |
| Purity : | >90% by SDS-PAGE & HPLC analyses |
| Notes : | Small volumes of ApoE3 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
| Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Gene Name : | ApoE3 |
| Official Symbol : | ApoE3 |
| Synonyms : | APOE; APOE; AD2; LPG; LDLCQ5; Apo-E; |
| Gene ID : | 348 |
| mRNA Refseq : | NM_000041.2 |
| Protein Refseq : | NP_000032.1 |
| MIM : | 104310 |
| UniProt ID : | P02649 |
| Chromosome Location : | Chromosome: 19; NC_000019.10 (44905782..44909393). Location: 19q13.2 |
| Function : | ?ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants |
Products Types
| ◆ Recombinant Protein | ||
| APOE-01H | Recombinant Human ApoE3 Protein | +Inquiry |
| APOE-04H | Recombinant Human ApoE3 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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