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Native Bovine NEFM

Cat.No. : NEFM-1520B
Product Overview : Ultra Pure NeuroFilament Protein having a Molecular mass of 160 kDa produced from Bovine Spinal Cord.
  • Specification
  • Gene Information
  • Related Products
Description : Neurofilaments are type IV intermediate filament heteropolymers that are composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber and may also have a role in intracellular transport to axons and dendrites. NeuroFilament 160kDa is a medium neurofilament protein, which is commonly used as a biomarker of neuronal damage.
Source : Bovine Spinal Cord
Species : Bovine
Form : The protein was lyophilized from a 1mg/ml solution containing 10mM sodium phosphate, pH-7.5, 2mM DTT, 6M urea and 1mM EDTA.Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Molecular Mass : 103,210 Da
Purity : Greater than 98.0% as determined by RP-HPLC and SDS-PAGE.
Applications : Protein standard in 1D and 2D SDS gelelectrophoresisImmunoassays Immunization.
Notes : Small volumes of NEFM native protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Reconstitution : It is recommended to reconstitute the lyophilized NEFM in sterile 18M Ω-cm H2O.
Warning : It is recommended to reconstitute the lyophilized NEFM in sterile 18M Omega -cm H2O.
Gene Name : NEFM neurofilament, medium polypeptide [ Bos taurus ]
Official Symbol : NEFM
Synonyms : NEF3; NF-M; neurofilament medium polypeptide; neurofilament 3; neurofilament M subunit; 160 kDa neurofilament protein; neurofilament triplet M protein; major neuronal intermediate filament subunit
Gene ID : 281347
mRNA Refseq : NM_001244145
Protein Refseq : NP_001231074
Chromosome Location : chromosome: 8
Pathway : Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem
Function : structural molecule activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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