Native Bovine NEFM

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Native Bovine NEFM

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Cat.No. : NEFM-1520B
Product Overview : Ultra Pure NeuroFilament Protein having a Molecular mass of 160 kDa produced from Bovine Spinal Cord.
Description : Neurofilaments are type IV intermediate filament heteropolymers that are composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber and may also have a role in intracellular transport to axons and dendrites. NeuroFilament 160kDa is a medium neurofilament protein, which is commonly used as a biomarker of neuronal damage.
Source : Bovine Spinal Cord
Species : Bovine
Form : The protein was lyophilized from a 1mg/ml solution containing 10mM sodium phosphate, pH-7.5, 2mM DTT, 6M urea and 1mM EDTA.Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Molecular Mass : 103,210 Da
Purity : Greater than 98.0% as determined by RP-HPLC and SDS-PAGE.
Applications : Protein standard in 1D and 2D SDS gelelectrophoresisImmunoassays Immunization.
Notes : Small volumes of NEFM native protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Reconstitution : It is recommended to reconstitute the lyophilized NEFM in sterile 18M Ω-cm H2O.
Warning : It is recommended to reconstitute the lyophilized NEFM in sterile 18M Omega -cm H2O.
Gene Name : NEFM neurofilament, medium polypeptide [ Bos taurus ]
Official Symbol : NEFM
Synonyms : NEF3; NF-M; neurofilament medium polypeptide; neurofilament 3; neurofilament M subunit; 160 kDa neurofilament protein; neurofilament triplet M protein; major neuronal intermediate filament subunit
Gene ID : 281347
mRNA Refseq : NM_001244145
Protein Refseq : NP_001231074
Chromosome Location : chromosome: 8
Pathway : Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem
Function : structural molecule activity

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