"NEFM" Related Products

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Native Bovine NEFM

Cat.No.: NEFM-1520B
Product Overview: Ultra Pure NeuroFilament Protein having a Molecular mass of 160 kDa produced from Bovine Spinal Cord.
Description: Neurofilaments are type IV intermediate filament heteropolymers that are composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber and may also have a role in intracellular transport to axons and dendrites. NeuroFilament 160kDa is a medium neurofilament protein, which is commonly used as a biomarker of neuronal damage.
Source: Bovine Spinal Cord
Species: Bovine
Form: The protein was lyophilized from a 1mg/ml solution containing 10mM sodium phosphate, pH-7.5, 2mM DTT, 6M urea and 1mM EDTA.Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Molecular Mass: 103,210 Da
Purity: Greater than 98.0% as determined by RP-HPLC and SDS-PAGE.
Applications: Protein standard in 1D and 2D SDS gelelectrophoresisImmunoassays Immunization.
Notes: Small volumes of NEFM native protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Reconstitution: It is recommended to reconstitute the lyophilized NEFM in sterile 18M Ω-cm H2O.
Warning: It is recommended to reconstitute the lyophilized NEFM in sterile 18M Omega -cm H2O.
Gene Name: NEFM neurofilament, medium polypeptide [ Bos taurus ]
Official Symbol: NEFM
Synonyms: NEF3; NF-M; neurofilament medium polypeptide; neurofilament 3; neurofilament M subunit; 160 kDa neurofilament protein; neurofilament triplet M protein; major neuronal intermediate filament subunit
Gene ID: 281347
mRNA Refseq: NM_001244145
Protein Refseq: NP_001231074
Chromosome Location: chromosome: 8
Pathway: Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem
Function: structural molecule activity

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