Recombinant Human MAP3K15, GST-tagged
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Cat.No. : | MAP3K15-44H |
Product Overview : | Recombinant human ASK3 (MAP3K15) (582-1169) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
Description : | ASK3 (MAP3K15) is a member of the mitogen-activated protein kinase (MAPK) family which functions in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. ASK3 plays an essential role in apoptotic cell death triggered by cellular stresses. ASK3 is also functions in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~93 kDa |
Applications : | Western Blot |
Storage : | Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1ug/ul |
Gene Name : | MAP3K15 mitogen-activated protein kinase kinase kinase 15 [ Homo sapiens ] |
Official Symbol : | MAP3K15 |
Synonyms : | MAP3K15; mitogen-activated protein kinase kinase kinase 15; bA723P2.3; FLJ16518; MEKK 15; MEK kinase 15; MAPK/ERK kinase kinase 15; apoptosis signal-regulating kinase 3; ASK3; |
Gene ID : | 389840 |
mRNA Refseq : | NM_001001671 |
Protein Refseq : | NP_001001671 |
MIM : | 300820 |
UniProt ID : | Q6ZN16 |
Chromosome Location : | Xp22.12 |
Function : | ATP binding; MAP kinase kinase kinase activity; metal ion binding; nucleotide binding; protein serine/threonine kinase activity; |
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MAP1LC3A MAP1LC3B MAP1LC3B2 Map2k1 MAP2K2 MAP2K3 MAP2K6 Map3k1 MAP3K14 MAP3K2 MAP3K3 MAP3K5 MAP3K8 MAP4K5 MAP2K4 MAP3K6 MAP2K5 MAP2K7 MAP3K11 MAP4K4 MAP4K2 MAP4K1 MAP1S Map2 MAP3K13 MAP3K15 MAP3K4 MAP3K7 MAP3K7IP1 MAP4 MAP3K10 MAP3K9 MAP1A MAP1B MAP7 MAP4K3 MAP3K12 MAP1LC3C MAP6D1 MAP7D1 MAP9 MAP6 MAP2K1IP1 MAP7D2 MAP7D3
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