Recombinant Human TIMP4, MIgG2a Fc-tagged

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Recombinant Human TIMP4, MIgG2a Fc-tagged

TIMP4 Related Products

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Cat.No. : TIMP4-3243H
Product Overview : The extracellular domain of human TIMP4(AAH10553.1)(Cys30-Pro224) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.
Description : This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrixmetalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted,netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation andrecruitment and may play role in hormonal regulation and endometrial tissue remodeling.
Source : CHO cell
Species : Human
Tag : MIgG2a Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by its ability to induce alkaline phosphatase production .
Molecular Mass : 48KDa (monomer)
AA Sequence : Cys30-Pro2 24
Endotoxin : <0.06 eu/μg as determined by lal>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : TIMP4 TIMP metallopeptidase inhibitor 4 [ Homo sapiens ]
Official Symbol : TIMP4
Synonyms : TIMP4; TIMP metallopeptidase inhibitor 4; tissue inhibitor of metalloproteinase 4; metalloproteinase inhibitor 4; TIMP-4; tissue inhibitor of metalloproteinases 4;
Gene ID : 7079
mRNA Refseq : NM_003256
Protein Refseq : NP_003247
MIM : 601915
UniProt ID : Q99727
Chromosome Location : 3p25
Pathway : Matrix Metalloproteinases, organism-specific biosystem;
Function : enzyme inhibitor activity; metal ion binding; metalloendopeptidase inhibitor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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