"TIMP4" Related Products


Recombinant Human TIMP4, MIgG2a Fc-tagged

Cat.No.: TIMP4-3243H
Product Overview: The extracellular domain of human TIMP4(AAH10553.1)(Cys30-Pro224) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.
Description: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrixmetalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted,netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation andrecruitment and may play role in hormonal regulation and endometrial tissue remodeling.
Source: CHO cell
Species: Human
Tag: MIgG2a Fc-tagged
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by its ability to induce alkaline phosphatase production .
Molecular Mass: 48KDa (monomer)
AA Sequence: Cys30-Pro224
Endotoxin: <0.06 eu/μg as determined by lal>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: TIMP4 TIMP metallopeptidase inhibitor 4 [ Homo sapiens ]
Official Symbol: TIMP4
Synonyms: TIMP4; TIMP metallopeptidase inhibitor 4; tissue inhibitor of metalloproteinase 4; metalloproteinase inhibitor 4; TIMP-4; tissue inhibitor of metalloproteinases 4;
Gene ID: 7079
mRNA Refseq: NM_003256
Protein Refseq: NP_003247
MIM: 601915
UniProt ID: Q99727
Chromosome Location: 3p25
Pathway: Matrix Metalloproteinases, organism-specific biosystem;
Function: enzyme inhibitor activity; metal ion binding; metalloendopeptidase inhibitor activity;

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