Recombinant Human BTN3A1, MIgG2a Fc-tagged BTN3A1-001H

Recombinant Human BTN3A1, MIgG2a Fc-tagged

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Recombinant Human BTN3A1, MIgG2a Fc-tagged

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Cat.No. : BTN3A1-001H
Product Overview : The extracellular domain of human CD277 (AAI21801.1) (Gln30-Gly254) is fused to the N-terminus of the Fc region of mouse IgG2awas expressed in CHO cell
Description : The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each
Source : CHO cells
Species : Human
Tag : MIgG2a Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Play a role in T-cell activation and in the adaptive immune response.
Molecular Mass : 51KDa (monomer)
AA Sequence : Gln30-Gly254
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : BTN3A1 butyrophilin, subfamily 3, member A1 [ Homo sapiens ]
Official Symbol : BTN3A1
Synonyms : BTN3A1; butyrophilin, subfamily 3, member A1; butyrophilin subfamily 3 member A1; BT3.1; BTF5; CD277; dJ45P21.3 (butyrophilin, subfamily 3, member A1); MGC141880;
Gene ID : 11119
mRNA Refseq : NM_001145008
Protein Refseq : NP_001138480
MIM : 613593
UniProt ID : O00481
Chromosome Location : 6p22.1
Function : protein binding;

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