Recombinant Full Length Human BTN3A1 Protein, C-Flag-tagged

• Cat.No.: BTN3A1-1530HFL
• Product Overview: Recombinant Full Length Human BTN3A1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene and the BTN2 and genes, which have undergone tandem duplication, resulting in 3 copies of each.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 57.5 kDa
• AA Sequence: MKMASFLAFLLLNFRVCLLLLQLLM PHSAQFSVLGPSGPILAMVGEDADL PCHLFPTMSAETMELKWVSS SLRQVVNVYADGKEVEDRQSAPYRG RTSILRDGITAGKAALRIHNVTASD SGKYLCYFQDGDFYEKALVE LKVAALGSDLHVDVKGYKDGGIHLE CRSTGWYPQPQIQWSNNKGENIPTV EAPVVADGVGLYAVAASVIM RGSSGEGVSCTIRSSLLGLEKTASI SIADPFFRSAQRWIAALAGTLPVLL LLLGGAGYFLWQQQEEKKTQ FRKKKREQELREMAWSTMKQEQSTR VKLLEELRWRSIQYASRGERHSAYN EWKKALFKPADVILDPKTAN PILLVSEDQRSVQRAKEPQDLPDNP ERFNWHYCVLGCESFISGRHYWEVE VGDRKEWHIGVCSKNVQRKG WVKMTPENGFWTMGLTDGNKYRTLT EPRTNLKLPKTPKKVGVFLDYETGD ISFYNAVDGSHIHTFLDVSF
  SEALYPVFRILTLEPTALTICPATR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Transmembrane

Gene Information

• Gene Name: BTN3A1 butyrophilin subfamily 3 member A1 [ Homo sapiens (human) ]
• Official Symbol: BTN3A1
• Synonyms: BTF5; BT3.1; CD277; BTN3.1
• Gene ID: 11119
• mRNA Refseq: NM_007048.6
• Protein Refseq: NP_008979.3
• MIM: 613593
• UniProt ID: O00481