Active Recombinant Human CD274, MIgG2a Fc-tagged
Cat.No. : | CD274-002H |
Product Overview : | The extracellular domain of human PDL1 (NP_054862.1) ( Phe19-Arg238) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell |
- Specification
- Gene Information
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Description : | CD274 (CD274 molecule) is a protein-coding gene. Diseases associated with CD274 include pulmonary venoocclusive disease, and htlv-1 associated myelopathy/tropical spastic paraparesis, and among its related super-pathways are Immune System and Phosphorylation of CD3 and TCR zeta chains. GO annotations related to this gene include protein binding |
Source : | CHO cells |
Species : | Human |
Tag : | MIgG2a Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to inhibit anti-CD3 antibody induced IL-2 secretion in human T lymphocytes. |
Molecular Mass : | 54 KDa (monomer) |
AA Sequence : | Phe19-Arg238 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | CD274 CD274 molecule [ Homo sapiens ] |
Official Symbol : | CD274 |
Synonyms : | CD274; CD274 molecule; CD274 antigen , PDCD1LG1, programmed cell death 1 ligand 1; programmed cell death 1 ligand 1; B7 homolog 1; B7 H; B7 H1; B7H1; PD L1; PDL1; CD274 antigen; PDCD1 ligand 1; programmed death ligand 1; B7-H; PD-L1; PDCD1L1; PDCD1LG1; MGC142294; MGC142296; |
Gene ID : | 29126 |
mRNA Refseq : | NM_014143 |
Protein Refseq : | NP_054862 |
MIM : | 605402 |
UniProt ID : | Q9NZQ7 |
Chromosome Location : | 9p24.1 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune System, organism-specific biosystem; PD-1 signaling, organism-specific biosystem; |
Function : | protein binding; protein tyrosine phosphatase activity; receptor activity; |
Products Types
◆ Recombinant Protein | ||
CD274-1081H | Recombinant Human CD274 protein(Met1-Thr239), His-tagged, Biotinylated | +Inquiry |
CD274-379H | Active Recombinant Human CD274 Protein, LIgG2b Fc-tagged, low endotoxin | +Inquiry |
CD274-708H | Recombinant Human CD274 Protein | +Inquiry |
CD274-1065C | Recombinant Cynomolgus/Rhesus CD274 protein(Met1-Thr239), His-tagged, Biotinylated | +Inquiry |
CD274-705H | Recombinant Human CD274 Protein, C13 and N15 Labeled | +Inquiry |
◆ Lysates | ||
CD274-2735HCL | Recombinant Human CD274 cell lysate | +Inquiry |
CD274-002RCL | Recombinant Rat CD274 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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