Recombinant Mouse ICAM1, MIgG2a Fc-tagged, mutant

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Recombinant Mouse ICAM1, MIgG2a Fc-tagged, mutant

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Cat.No. : ICAM1-317M
Product Overview : The extracellular domain of mouse CD54 [ICAM-1] (AAH08626.1) (Gln28-Asn485) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a was expressed in CHO cell.
Description : This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of theimmune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus asa receptor
Source : CHO cell
Species : Mouse
Tag : MIgG2a Fc-tagged, mutant
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells.
AA Sequence : Gln28-Asn4 85
Endotoxin : <0.06 eu/μg as determined by lal>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : Icam1 intercellular adhesion molecule 1 [ Mus musculus ]
Official Symbol : ICAM1
Synonyms : ICAM1; intercellular adhesion molecule 1; myD10; CD54; Ly-47; Icam-1; MALA-2; MGC6195;
Gene ID : 15894
mRNA Refseq : NM_010493
Protein Refseq : NP_034623
Pathway : Adaptive Immune System, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;
Function : cell surface binding; integrin binding; protein complex binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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