Active Recombinant Mouse ICAM1, MIgG2a Fc-tagged, mutant

• Cat.No.: ICAM1-317M
• Product Overview: The extracellular domain of mouse CD54 [ICAM-1] (AAH08626.1) (Gln28-Asn485) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a was expressed in CHO cell.

Specification

• Description: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of theimmune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus asa receptor
• Source: CHO cell
• Species: Mouse
• Tag: MIgG2a Fc-tagged, mutant
• Form: Lyophilized from 0.2μm-filtered solution in PBS.
• Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells.
• AA Sequence: Gln28-Asn485
• Endotoxin: <0.06 eu/μg as determined by lal>
• Purity: >98%, by SDS-PAGE under reducing conditions.
• Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
• Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
• Warning: Avoid freeze/thaw cycles.

Gene Information

• Gene Name: Icam1 intercellular adhesion molecule 1 [ Mus musculus ]
• Official Symbol: ICAM1
• Synonyms: ICAM1; intercellular adhesion molecule 1; myD10; CD54; Ly-47; Icam-1; MALA-2; MGC6195
• Gene ID: 15894
• mRNA Refseq: NM_010493
• Protein Refseq: NP_034623
• Pathway: Adaptive Immune System, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem
• Function: cell surface binding; integrin binding; protein complex binding