Recombinant Mouse ICAM1, MIgG2a Fc-tagged, mutant

Cat.No.: ICAM1-317M
Product Overview: The extracellular domain of mouse CD54 [ICAM-1] (AAH08626.1) (Gln28-Asn485) is fused to the N-terminus of the Fc region of a mutant mouse IgG2a was expressed in CHO cell.
Description: This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of theimmune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus asa receptor
Source: CHO cell
Species: Mouse
Tag: MIgG2a Fc-tagged, mutant
Form: Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity: Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells.
AA Sequence: Gln28-Asn485
Endotoxin: <0.06 eu/μg as determined by lal>
Purity: >98%, by SDS-PAGE under reducing conditions.
Stability: Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution: Reconstitute at 100μg/ml in sterile PBS.
Warning: Avoid freeze/thaw cycles.
Gene Name: Icam1 intercellular adhesion molecule 1 [ Mus musculus ]
Official Symbol: ICAM1
Synonyms: ICAM1; intercellular adhesion molecule 1; myD10; CD54; Ly-47; Icam-1; MALA-2; MGC6195;
Gene ID: 15894
mRNA Refseq: NM_010493
Protein Refseq: NP_034623
Pathway: Adaptive Immune System, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;
Function: cell surface binding; integrin binding; protein complex binding;

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