Recombinant Human HIST1H1C, GST-tagged

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Recombinant Human HIST1H1C, GST-tagged

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Cat.No. : HIST1H1C-210H
Product Overview : Human HIST1H1C full-length protein ( NP_005310.1, 1 a.a. - 213 a.a.) was expressed with a GST tag at the N-terminal.
Description : Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 47.8 kDa
AA Sequence : MSETAPAAPA AAPPAEKAPV KKKAAKKAGG TPRKASGPPV SELITKAVAA SKERSGVSLA ALKKALAAAG YDVEKNNSRI KLGLKSLVSK GTLVQTKGTG ASGSFKLNKK AASGEAKPKV KKAGGTKPKK PVGAAKKPKK AAGGATPKKS AKKTPKKAKK PAAATVTKKV AKSPKKAKVA KPKKAAKSAA KAVKPKAAKP KVVKPKKAAP KKK
Stability : Best use within three months from the date of receipt of this protein.
Storage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Gene Name : HIST1H1C histone cluster 1, H1c [ Homo sapiens ]
Official Symbol : HIST1H1C
Synonyms : HIST1H1C; histone cluster 1, H1c; H1 histone family, member 2 , H1F2, histone 1, H1c; histone H1.2; H1.2; H1c; H1s 1; histone H1d; histone 1, H1c; H1 histone family, member 2; H1C; H1F2; MGC3992;
Gene ID : 3006
mRNA Refseq : NM_005319
Protein Refseq : NP_005310
MIM : 142710
UniProt ID : P16403
Chromosome Location : 6p21.3
Pathway : Activation of DNA fragmentation factor, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis induced DNA fragmentation, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem;
Function : DNA binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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