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Recombinant Human PTPRE 293 Cell Lysate

Cat.No. : PTPRE-2676HCL
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  • Gene Information
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Description : Antigen standard for protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 2 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
Source : HEK 293 cells
Species : Human
Components : This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
Size : 0.1 mg
Storage Instruction : Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
Applications : ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.
Gene Name : PTPRE protein tyrosine phosphatase, receptor type, E [ Homo sapiens ]
Official Symbol : PTPRE
Synonyms : PTPRE; protein tyrosine phosphatase, receptor type, E; receptor-type tyrosine-protein phosphatase epsilon; PTPE; protein tyrosine phosphatase, receptor type, epsilon polypeptide; HPTPE; FLJ57799; FLJ58245; R-PTP-EPSILON; DKFZp313F1310;
Gene ID : 5791
mRNA Refseq : NM_130435
Protein Refseq : NP_569119
MIM : 600926
UniProt ID : P23469
Chromosome Location : 10q26
Function : hydrolase activity; protein binding; protein homodimerization activity; protein tyrosine phosphatase activity; receptor activity; transmembrane receptor protein tyrosine phosphatase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does PTPRE protein regulate cell signaling pathways? 01/10/2023

PTPRE protein acts as a phosphatase, dephosphorylating specific substrates involved in cell signaling, thereby modulating various cellular processes.

What types of cancer have shown a significant association with PTPRE protein dysregulation? 08/25/2022

Breast cancer, colorectal cancer, and prostate cancer are among the malignancies in which PTPRE protein dysregulation has been implicated.

How does PTPRE protein function in the nervous system? 02/21/2019

PTPRE protein plays a role in synaptic plasticity and neuronal development, and its dysregulation has been implicated in neurodegenerative diseases.

Can PTPRE protein inhibitors have potential side effects in clinical treatment? 11/16/2016

While PTPRE inhibitors may have off-target effects, research is focused on developing selective inhibitors to minimize potential adverse effects.

Are there any clinical trials targeting PTPRE protein in cancer treatment? 09/01/2016

Clinical trials evaluating the efficacy of PTPRE inhibitors in cancer therapy are currently underway, with promising early results.

Customer Reviews (3)

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Reviews
01/26/2021

    Whether utilized in protein-protein interaction studies or enzymatic assays, this protein exhibits robust performance, enabling accurate data generation and analysis.

    05/21/2020

      the PTPRE protein has demonstrated its efficacy in protein electron microscopy structure analysis.

      03/11/2018

        This cutting-edge technique allows for the visualization and characterization of protein structures at the atomic level, providing insights into their function and potential therapeutic targets.

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