Recombinant Human Mitogen-activated Protein Kinase 9, His-tagged

PRODUCTS

Home / Products / Recombinant Proteins / Recombinant Human Mitogen-activated Protein Kinase 9, His-tagged

Recombinant Human Mitogen-activated Protein Kinase 9, His-tagged

MAPK9 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat. No. : MAPK9-44H
Product Overview : Recombinant Human JNK2 produced inE.coliis a soluble 48 kDa protein that is activated in response to cellular stress, radiation and growth factors. This protein is the full-length form of the protein with a C-terminal His-tagged (His-tag on COOH terminus).
Description : JUN N-terminal Kinase 2 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene"s mouse counterpart suggest a key role in T-cell differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Source : Escherichia Coli.
Amino Acid Sequence : MSDSKCDSQF YSVQVADSTF TVLKRYQQLK PIGSGAQGIV CAAFDTVLGI NVAVKKLSRP FQNQTHAKRA YRELVLLKCV NHKNIISLLN VFTPQKTLEE FQDVYLVMEL MDANLCQVIH MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTACTNF MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMGELVK GCVIFQGTDH IDQWNKVIEQ LGTPSAEFMK KLQPTVRNYV ENRPKYPGIK FEELFPDWIF PSESERDKIK TSQARDLLSK MLVIDPDKRI SVDEALRHPY ITVWYDPAEA EAPPPQIYDA QLEEREHAIE EWKELIYKEV MDWEERSKNG VVKDQPSDAA VSSNATPSQS SSINDISSMS TEQTLASDTD SSLDASTGPL EGCRGGGSHH HHHH
Purity : Greater than 85% as determined by SDS-PAGE. Mass spectrometry of tryptic digest products for identity determination.
Physical Appearance : Sterile Filtered clear solution.
Formulation : 25mM HEPES at pH 8.0, 150mM NaCl, 2mM DTT and 10% glycerol.
Unit Definition : Activity is approximately 200 units/mg. A certificate of analysis is provided, stating the enzymatic activity for each production lot. 1.0 unit of activity is defined as the amount of enzyme required to catalyze the transfer of 1.0 nmole of phosphate from ATP to to a protein substrate per minute at 30ºC.
Storage : Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Gene Name : MAPK9 mitogen-activated protein kinase 9 [ Homo sapiens ]
Synonyms : MAPK9; mitogen-activated protein kinase 9; JNK2; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; JNK2BETA; p54aSAPK; JNK2ALPHA; Jun kinase; ; MAP kinase 9; c-Jun kinase 2; OTTHUMP00000161542; OTTHUMP00000161543; c-Jun N-terminal kinase 2; stress-activated protein kinase JNK2; mitogen-activated protein kinase 9 isoform JNK2 alpha2; EC 2.7.11.24; Mitogen-activated protein kinase 9; Stress-activated protein kinase JNK2
Gene ID : 5601
mRNA Refseq : NM_001135044
Protein Refseq : NP_001128516
MIM : 602896
UniProt ID : P45984
Chromosome Location : 5q35
Pathway : Adipocytokine signaling pathway; Colorectal cancer; Epithelial cell signaling in Helicobacter pylori infection; ErbB signaling pathway; Fc epsilon RI signaling pathway; Focal adhesion; GnRH signaling pathway; Insulin signaling pathway; MAPK signaling pathway; Neurotrophin signaling pathway; Pancreatic cancer; Pathways in cancer; RIG-I-like receptor signaling pathway; T cell receptor signaling pathway; Toll-like receptor signaling pathway; Type II diabetes mellitus; Wnt signaling pathway
Function : ATP binding; JUN kinase activity; MAP kinase activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Verification Code Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2021 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy